Surface chemistry of gold nanoparticles for health-related applications

J Zhang, L Mou, X Jiang - Chemical Science, 2020 - pubs.rsc.org
Functionalization of gold nanoparticles is crucial for the effective utilization of these materials
in health-related applications. Health-related applications of gold nanoparticles rely on the …

The emergence of Zika virus and its new clinical syndromes

TC Pierson, MS Diamond - Nature, 2018 - nature.com
Zika virus (ZIKV) is a mosquito-transmitted flavivirus that has emerged as a global health
threat because of its potential to generate explosive epidemics and ability to cause …

[HTML][HTML] Human neutralizing antibodies against SARS-CoV-2 require intact Fc effector functions for optimal therapeutic protection

ES Winkler, P Gilchuk, J Yu, AL Bailey, RE Chen… - Cell, 2021 - cell.com
SARS-CoV-2 has caused the global COVID-19 pandemic. Although passively delivered
neutralizing antibodies against SARS-CoV-2 show promise in clinical trials, their mechanism …

The safety and immunogenicity of two Zika virus mRNA vaccine candidates in healthy flavivirus baseline seropositive and seronegative adults: the results of two …

B Essink, L Chu, W Seger, E Barranco… - The Lancet Infectious …, 2023 - thelancet.com
Background Developing a safe and immunogenic vaccine against Zika virus remains an
unmet medical need. We did two phase 1 studies that evaluated the safety and …

[HTML][HTML] Modified mRNA vaccines protect against Zika virus infection

JM Richner, S Himansu, KA Dowd, SL Butler, V Salazar… - Cell, 2017 - cell.com
The emergence of ZIKV infection has prompted a global effort to develop safe and effective
vaccines. We engineered a lipid nanoparticle (LNP) encapsulated modified mRNA vaccine …

Zika virus pathogenesis and tissue tropism

JJ Miner, MS Diamond - Cell host & microbe, 2017 - cell.com
Although Zika virus (ZIKV) was isolated approximately 70 years ago, few experimental
studies had been published prior to 2016. The recent spread of ZIKV to countries in the …

Zika virus structure, maturation, and receptors

D Sirohi, RJ Kuhn - The Journal of infectious diseases, 2017 - academic.oup.com
The emergence of Zika virus (ZIKV) as a major public health threat has focused research on
understanding virus biology and developing a suite of strategies for disease intervention …

[HTML][HTML] Recurrent potent human neutralizing antibodies to Zika virus in Brazil and Mexico

DF Robbiani, L Bozzacco, JR Keeffe, R Khouri… - Cell, 2017 - cell.com
Antibodies to Zika virus (ZIKV) can be protective. To examine the antibody response in
individuals who develop high titers of anti-ZIKV antibodies, we screened cohorts in Brazil …

Passive immunotherapy of viral infections:'super-antibodies' enter the fray

LM Walker, DR Burton - Nature Reviews Immunology, 2018 - nature.com
Antibodies have been used for more than 100 years in the therapy of infectious diseases,
but a new generation of highly potent and/or broadly cross-reactive human monoclonal …

Immune response to dengue and Zika

A Elong Ngono, S Shresta - Annual review of immunology, 2018 - annualreviews.org
Flaviviruses such as dengue (DENV), yellow fever (YFV), West Nile (WNV), and Zika (ZIKV)
are human pathogens of global significance. In particular, DENV causes the most prevalent …