Alcohol use disorder (AUD) is a chronic, relapsing disorder characterized by an escalation
of drinking and the emergence of negative affective states over time. Within this framework …

Skeletal muscle dysfunction is highly prevalent and is one of the earliest pathological tissue
changes among people with at-risk alcohol use. Clinical studies to elucidate …

Alcohol use disorder (AUD) is a chronic neurobehavioral condition characterized by a cycle
of tolerance development, increased consumption, and reinstated craving and seeking …

Opioids are commonly prescribed for pain despite growing evidence of their low efficacy in
the treatment of chronic inflammatory pain and the high potential for misuse. There is a clear …

Excessive binge alcohol intake is a common drinking pattern in humans, especially during
holidays. Cessation of the binge drinking often leads to aberrant withdrawal behaviors, as …

Aims Alcohol abuse has attracted public attention and chronic alcohol exposure can result in
irreversible structural changes in the brain. The molecular mechanisms underlying alcohol …

目的探讨长时间大量饮用不同乙醇含量的饮料对小鼠海马内参与自噬的哺乳动物雷帕霉素靶
蛋白(mTOR) 及c-JunN 末端激酶(JNK) 通路的影响, 揭示含乙醇饮料对认知功能的影响及机制 …

Background: High expression of PIN1 is associated with gastric cancer progression and risk.
Patients & methods: Two single-nucleotide polymorphisms in PIN1, rs2233678 and …

Alcohol use disorder (AUD) is a chronic, relapsing disorder characterized by an escalation
of drinking and the emergence of negative affective states over time. Within this framework …