Today, persistent and uncontrolled inflammation is appreciated to play a pivotal role in many
diseases, such as cardiovascular diseases, neurodegenerative diseases, metabolic …

Interactions between the immune and nervous systems are of central importance in
neuropathic pain, a common and debilitating form of chronic pain caused by a lesion or …

Pathological pain can be initiated after inflammation and/or peripheral nerve injury. It is a
consequence of the pathological functioning of the nervous system rather than only a …

Objective To determine whether dietary interventions that increase n-3 fatty acids with and
without reduction in n-6 linoleic acid can alter circulating lipid mediators implicated in …

With osteoarthritis being the most common degenerative disease in pet animals, a very
broad panel of natural health products is available on the market for its management. The …

Inflammation is an essential action to protect the host human body from external, harmful
antigens and microorganisms. However, an excessive inflammation reaction sometimes …

Abstract Maresin-2 (MaR2) is a specialized pro-resolution lipid mediator (SPM) that reduces
neutrophil recruitment in zymosan peritonitis. Here, we investigated the analgesic effect of …

Neuropathic pain (NP) is a chronic condition that results from a lesion or disease of the
nervous system, greatly impacting patients' quality of life. Current pharmacotherapy options …

Chronic pain is a refractory health disease worldwide causing an enormous economic
burden on individuals and society. Accumulating evidence suggests that inflammation in the …

Background and Purpose Gouty arthritis is characterized by an intense inflammatory
response to monosodium urate crystals (MSU), which induces severe pain. Current …