Recent patents of pharmaceutical co-crystals: product development on anti-cancer drugs and beyond
AAMS Tharik, SN Meyyanathan - Recent Patents on Anti-Cancer …, 2023 - benthamdirect.com
Background: Scientists, academicians, and researchers from academics and the
pharmaceutical industries have all expressed interest in the design and production of …
pharmaceutical industries have all expressed interest in the design and production of …
[PDF][PDF] Hot melt extrusion in engineering of drug cocrystals: a review
Crystal engineering technique has been widely explored in recent times to bring about
changes in crystallinity which aids to achieve various goals such as solubility enhancement …
changes in crystallinity which aids to achieve various goals such as solubility enhancement …
[PDF][PDF] Mefenamic acid-nicotinamide co-crystal synthesized by using melt crystallization method and its solubility study
Objective: The focus of this study is to develop the formation mefenamic acid (MFA)-
nicotinamide (NCT) co-crystal by using melt crystallization method and investigate its …
nicotinamide (NCT) co-crystal by using melt crystallization method and investigate its …
[PDF][PDF] Systematic review: co-crystal as efforts to improve physicochemical and bioavailability properties of oral solid dosage form
I Sopyan, B Alvin, KS Insan Sunan… - Int. J. Appl …, 2021 - researchgate.net
Water solubility and low bioavailability of active pharmaceutical ingredients are some of the
main challenges in the process of developing new drugs, especially drugs in oral solid …
main challenges in the process of developing new drugs, especially drugs in oral solid …
Co-crystallization of Hesperidin with different co-formers to enhance solubility, antioxidant and anti-inflammatory activities
Hesperidin (HSP) is a natural flavonoid glycoside with very low aqueous solubility and a
slow dissolution rate, limiting its effectiveness. This study aims to address these issues by …
slow dissolution rate, limiting its effectiveness. This study aims to address these issues by …
[PDF][PDF] Development of binary and ternary complex of cefuroxime axetil with cyclodextrin for improving pharmaceutical characteristics
Objective: The current research objective is systematic development and characterization of
binary and ternary inclusion complexes of cefuroxime axetil with β-cyclodextrin to improve its …
binary and ternary inclusion complexes of cefuroxime axetil with β-cyclodextrin to improve its …
[PDF][PDF] Increasing solution in the drug simvastatin with solid dispersion technique using polymer Soluplus
Objective: Simvastatin is a bioactive compound belonging to the class II Biopharmaceutic
Classification System (BSC), which has high permeability but low solubility. The low …
Classification System (BSC), which has high permeability but low solubility. The low …
[PDF][PDF] Improvement of simvastatin dissolution rate using derivative non-covalent approach by solvent drop grinding method
Objective: This study aimed to enhance the solubility of simvastatin using noncovalent
derivatives (NCDs) with oxalic acid (OA), fumaric acid (AF), and nicotinamide (NK) as …
derivatives (NCDs) with oxalic acid (OA), fumaric acid (AF), and nicotinamide (NK) as …
Insightful Investigative Account on Hydrotropic Solubilization Practice Utilized for Solubility Management of Poorly Dissolvable Drugs
Background: Executing the centralization of medication in the foundational flow for
approaching their pharmacological has necessitated studying a vital parameter, ie solubility …
approaching their pharmacological has necessitated studying a vital parameter, ie solubility …
[PDF][PDF] Method Validation of Simvastatin in Pcl-Peg-Pcl Triblock Copolymer Micelles Using Uv-Vis Spectrophotometric for Solubility Enhancement Assay
METHOD VALIDATION OF SIMVASTATIN IN PCL-PEG-PCL TRIBLOCK COPOLYMER MICELLES
USING UV-VIS SPECTROPHOTOMETRIC FOR SOLUBILITY ENHAN Page 1 246 METHOD …
USING UV-VIS SPECTROPHOTOMETRIC FOR SOLUBILITY ENHAN Page 1 246 METHOD …