Stealth and pseudo-stealth nanocarriers
The stealth effect plays a central role on capacitating nanomaterials for drug delivery
applications through improving the pharmacokinetics such as blood circulation …
applications through improving the pharmacokinetics such as blood circulation …
Drug delivery to the central nervous system
Despite the rising global incidence of central nervous system (CNS) disorders, CNS drug
development remains challenging, with high costs, long pathways to clinical use and high …
development remains challenging, with high costs, long pathways to clinical use and high …
The use of alternative strategies for enhanced nanoparticle delivery to solid tumors
M Izci, C Maksoudian, BB Manshian… - Chemical …, 2021 - ACS Publications
Nanomaterial (NM) delivery to solid tumors has been the focus of intense research for over a
decade. Classically, scientists have tried to improve NM delivery by employing passive or …
decade. Classically, scientists have tried to improve NM delivery by employing passive or …
Targeting strategies for tissue-specific drug delivery
Off-target effects of systemically administered drugs have been a major hurdle in designing
therapies with desired efficacy and acceptable toxicity. Developing targeting strategies to …
therapies with desired efficacy and acceptable toxicity. Developing targeting strategies to …
The ancillary effects of nanoparticles and their implications for nanomedicine
Nanoparticles are often engineered as a scaffolding system to combine targeting, imaging
and/or therapeutic moieties into a unitary agent. However, mostly overlooked, the …
and/or therapeutic moieties into a unitary agent. However, mostly overlooked, the …
Biomedical polymers: synthesis, properties, and applications
Biomedical polymers have been extensively developed for promising applications in a lot of
biomedical fields, such as therapeutic medicine delivery, disease detection and diagnosis …
biomedical fields, such as therapeutic medicine delivery, disease detection and diagnosis …
Enhanced tumour penetration and prolonged circulation in blood of polyzwitterion–drug conjugates with cell-membrane affinity
S Chen, Y Zhong, W Fan, J Xiang, G Wang… - Nature Biomedical …, 2021 - nature.com
Effective anticancer nanomedicines need to exhibit prolonged circulation in blood, to
extravasate and accumulate in tumours, and to be taken up by tumour cells. These …
extravasate and accumulate in tumours, and to be taken up by tumour cells. These …
Advances in drug delivery systems based on red blood cells and their membrane-derived nanoparticles
Red blood cells (RBCs) and RBC membrane-derived nanoparticles have been historically
developed as bioinspired drug delivery systems to combat the issues of premature …
developed as bioinspired drug delivery systems to combat the issues of premature …
Engineering nano-drug biointerface to overcome biological barriers toward precision drug delivery
S Waheed, Z Li, F Zhang, A Chiarini, U Armato… - Journal of …, 2022 - Springer
The rapid advancement of nanomedicine and nanoparticle (NP) materials presents novel
solutions potentially capable of revolutionizing health care by improving efficacy …
solutions potentially capable of revolutionizing health care by improving efficacy …
Emerging blood–brain-barrier-crossing nanotechnology for brain cancer theranostics
Brain cancer, especially the most common type of glioblastoma, is highly invasive and
known as one of the most devastating and deadly neoplasms. Despite surgical and medical …
known as one of the most devastating and deadly neoplasms. Despite surgical and medical …