Abstract Ethnopharmacological relevance Traditional Chinese medicine has gained
significant attention in recent years owing to its multi-component, multi-target, and multi …

To improve the initiation and speed of intended action, one of the crucial mechanisms is
suppressing unwanted movements that interfere with goal-directed behavior, which is …

Background Parkinson's disease (PD) is the second most common neurodegenerative
disease in middle-aged and elderly populations, whereas there is no cure for PD so far …

c-Jun N-terminal kinases (JNKs) are involved in the pathogenesis of various diseases. In
particular, JNK3 and not JNK1/2 is primarily expressed in the brain and plays a key role in …

Background Parkinson's disease (PD) is a common, complex, and chronic
neurodegenerative disorder involved in multi-system. At present, medicine for PD has many …

Parkinson's disease is a multisystemic neurodegenerative disorder that includes motor and
non-motor symptoms, and common symptoms include memory loss and learning difficulties …

When WWOX is downregulated in middle age, aggregation of a protein cascade, including
TRAPPC6AΔ (TPC6AΔ), TIAF1, and SH3GLB2, may start to occur, and the event lasts more …

Parkinson's disease (PD) is a common neurodegenerative disorder characterized by the
loss of dopaminergic neurons in the substantia nigra pars compacta. The development of …

Polyphenols have been reported to have a multi-targeted neuroprotective effect on
Parkinson's disease (PD). However, there has been no comprehensive analysis of the effect …

Puerarin, a monomer of traditional Chinese medicine, is a key component of Pueraria radix.
Both clinical and experimental researches demonstrated that puerarin has therapeutic …