[HTML][HTML] Innate immunity drives pathogenesis of rheumatoid arthritis

MI Edilova, A Akram, AA Abdul-Sater - Biomedical Journal, 2021 - Elsevier
Rheumatoid arthritis (RA) is an autoimmune disease affecting∼ 1% of the general
population. This disease is characterized by persistent articular inflammation and joint …

The role of glucocorticoids in inflammatory diseases

SD Reichardt, A Amouret, C Muzzi, S Vettorazzi… - Cells, 2021 - mdpi.com
For more than 70 years, glucocorticoids (GCs) have been a powerful and affordable
treatment option for inflammatory diseases. However, their benefits do not come without a …

Identifying immune cell infiltration and effective diagnostic biomarkers in rheumatoid arthritis by bioinformatics analysis

S Zhou, H Lu, M Xiong - Frontiers in immunology, 2021 - frontiersin.org
Background Rheumatoid arthritis (RA) is a chronic systemic autoimmune disorder
characterized by inflammatory cell infiltration, leading to persistent synovitis and joint …

From rheumatoid factor to anti-citrullinated protein antibodies and anti-carbamylated protein antibodies for diagnosis and prognosis prediction in patients with …

CY Wu, HY Yang, SF Luo, JH Lai - International Journal of Molecular …, 2021 - mdpi.com
Rheumatoid arthritis (RA) is a chronic systemic inflammatory disease mainly involving
synovial inflammation and articular bone destruction. RA is a heterogeneous disease with …

Th17 cell pathogenicity and plasticity in rheumatoid arthritis

P Yang, FY Qian, MF Zhang, AL Xu… - Journal of leukocyte …, 2019 - academic.oup.com
CD4+ Th cells play an important role in the development of rheumatoid arthritis (RA) by
regulating adaptive immune response. As major subsets of CD4+ Th cells, Th17 cells can …

Natural medicines of targeted rheumatoid arthritis and its action mechanism

X Liu, Z Wang, H Qian, W Tao, Y Zhang, C Hu… - Frontiers in …, 2022 - frontiersin.org
Rheumatoid arthritis (RA) is an autoimmune disease involving joints, with clinical
manifestations of joint inflammation, bone damage and cartilage destruction, joint …

The burden of rheumatoid arthritis: findings from the 2019 global burden of diseases study and forecasts for 2030 by Bayesian age-period-cohort analysis

Y Cai, J Zhang, J Liang, M Xiao, G Zhang… - Journal of clinical …, 2023 - mdpi.com
Background: Rheumatoid arthritis (RA) is a key health issue worldwide. Due to early
identification and effective treatment strategies, the disease pattern of RA has also changed …

Transformation of fibroblast‐like synoviocytes in rheumatoid arthritis; from a friend to foe

MJ Mousavi, J Karami, S Aslani, MN Tahmasebi… - Autoimmunity …, 2021 - Springer
Swelling and the progressive destruction of articular cartilage are major characteristics of
rheumatoid arthritis (RA), a systemic autoimmune disease that directly affects the synovial …

When things go wrong: exploring possible mechanisms driving the progressive fibrosis phenotype in interstitial lung diseases

M Selman, A Pardo - European Respiratory Journal, 2021 - Eur Respiratory Soc
Interstitial lung diseases (ILDs) comprise a large and heterogeneous group of disorders of
known and unknown aetiology characterised by diffuse damage of the lung parenchyma. In …

Destructive roles of fibroblast-like synoviocytes in chronic inflammation and joint damage in rheumatoid arthritis

M Masoumi, H Bashiri, H Khorramdelazad… - Inflammation, 2021 - Springer
Fibroblast-like synoviocytes (FLSs) are important non-immune cells located mostly in the
inner layer of the synovium. Indeed, these cells are specialized mesenchymal cells …