In the modern era of advanced technologies, rapid and accurate analyses are needed, both
for scientific research and for industrial applications. For this reason, the Surface Plasmon …

Tau neuronal and glial pathologies drive the clinical presentation of Alzheimer's disease
and related human tauopathies. There is a growing body of evidence indicating that …

The past decade has seen researchers develop and apply novel technologies for
biomolecular detection, at times approaching hard limits imposed by physics and chemistry …

Carbonic anhydrase (CA, EC 4.2. 1.1) is a protein that is especially well-suited to serve as a
model in many types of studies in biophysics, bioanalysis, the physical-organic chemistry of …

Monitoring the binding affinities and kinetics of protein interactions is important in clinical
diagnostics and drug development because such information is used to identify new …

The quality of optical biosensor data must be improved in order to characterize the
mechanism and rate constants associated with molecular interactions. Many of the artifacts …

We examine through analytical calculations and finite element simulations how the detection
efficiency of disk and wire-like biosensors in unmixed fluids varies with size from the …

The number and diversity of surface plasmon resonance (SPR) biosensor applications
continue to increase. Evolutions in instrument and sensor chip technology, experimental …

During last decade there has been significant progress in the development of analytical
techniques for evaluation of receptor-ligand iteraction. Surface plasmon resonance (SPR) …

Packaging DNA into condensed structures is integral to the transmission of genomes. The
mammalian mitochondrial genome (mtDNA) is a high copy, maternally inherited genome in …