The family of VPS10p-Domain (D) receptors comprises five members named SorLA, Sortilin,
SorCS1, SorCS2 and SorCS3. While their physiological roles remain incompletely resolved …

Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal dementia (FDT) are progressive
neurodegenerative disorders that, in several cases, overlap in clinical presentation, and …

Frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS) are severely
debilitating and progressive neurodegenerative disorders. A distinctive pathological feature …

Alzheimer's disease (AD) is a progressive neurological disorder that affects the central
nervous system (CNS), leading to memory and cognitive decline. In AD, the brain …

Sustained exposures to ubiquitous outdoor/indoor fine particulate matter (PM2. 5), including
combustion and friction ultrafine PM (UFPM) and industrial nanoparticles (NPs) starting in …

The biomarkers era grew in the last two decades when several technical and
methodological advances have improved the research in neurodegenerative diseases. All …

Environmental exposures to fine particulate matter (PM2. 5) and ultrafine particle matter
(UFPM) are associated with overlapping Alzheimer's, Parkinson's and TAR DNA-binding …

In the last two decades, our knowledge of synaptic proteomes and their relationship to
normal brain function and neuropsychiatric disorders has been expanding rapidly through …

Background To date, migraine is diagnosed exclusively based on clinical criteria, but fluid
biomarkers are desirable to gain insight into pathophysiological processes and inform …

This Review emphasizes the impact of APOE4—the most significant genetic risk factor for
Alzheimer's disease (AD)—on peripheral and neural effects starting in childhood. We …