Evaluation of the human genome suggests that all members of the connexin family of gap-
junction proteins have now been successfully identified. This large and diverse family of …

In vertebrates, a family of related proteins called connexins form gap junctions (GJs), which
are intercellular channels. In the central nervous system (CNS), GJs couple …

This review is based in part on a roundtable discussion session:“Physiological roles for
heterotypic/heteromeric channels” at the 2013 International Gap Junction Conference (IGJC …

Despite concerted clinical and research efforts, cancer is a leading cause of death
worldwide. Surgery, radiation, and chemotherapy have remained the most common …

Gap-junction channels connect the cytoplasm of adjacent cells, allowing the diffusion of ions
and small metabolites. They are formed at the appositional plasma membranes by a family …

The epidermis (containing primarily ker‐atinocytes and melanocytes) overlies the dermis
(containing primarily fibroblasts) of human skin. We previously reported that dickkopf 1 …

Gap junctions are intercellular plasma membrane domains enriched in channels that allow
direct exchange of ions and small molecules between adjacent cells. Gap junction channels …

Paracellular barrier properties of tissues are mainly determined by the composition of
claudin heteropolymers. To analyze the molecular organization of tight junctions (TJ), we …

CNS glia and neurons express connexins, the proteins that form gap junctions in
vertebrates. We review the connexins expressed by oligodendrocytes and astrocytes, and …

Gap junctions (GJs) are aqueous channels that allow cells to communicate via physiological
signals directly. The role of gap junctional connectivity in determining single‐cell functions …