An RNA-centric view of transcription and genome organization

JE Henninger, RA Young - Molecular Cell, 2024 - cell.com
Foundational models of transcriptional regulation involve the assembly of protein complexes
at DNA elements associated with specific genes. These assemblies, which can include …

Neurodevelopmental functions and activities of the KAT3 class of lysine acetyltransferases

AK Shahib, M Rastegar, AJ van Wijnen… - Biochemistry and Cell …, 2024 - cdnsciencepub.com
The human lysine acetyltransferases KAT3A (CREBBP) and KAT3B (EP300) are essential
enzymes in gene regulation in the nucleus. Their ubiquitous expression in metazoan cell …

Enhancer Enh483 regulates myoblast proliferation and differentiation of buffalo myoblasts by targeting FAXC

Y Chen, J Zhao, C Zhong, Y Kang, Z Xiong… - Cell and Tissue …, 2024 - Springer
A detailed understanding of the precise regulatory mechanisms governing buffalo skeletal
muscle is crucial for improving meat quality and yield. Proper skeletal muscle fate decisions …

[HTML][HTML] Potential Transcriptional Enhancers in Coronaviruses: From Infectious Bronchitis Virus to SARS-CoV-2

R Patarca, WA Haseltine - International Journal of Molecular Sciences, 2024 - mdpi.com
Coronaviruses constitute a global threat to human and animal health. It is essential to
investigate the long-distance RNA-RNA interactions that approximate remote regulatory …

Dynamic modulation of enhancer‐promoter and promoter‐promoter connectivity in gene regulation

S Makino, T Fukaya - BioEssays, 2024 - Wiley Online Library
Enhancers are short segments of regulatory DNA that control when and in which cell‐type
genes should be turned on in response to a variety of extrinsic and intrinsic signals. At the …

Role of 3D chromatin conformation in gene regulation at the pupal stage and in the adult brain of Drosophila melanogaster

M Bardou - 2024 - hal.science
The genome of eukaryotic cells exhibits a highly hierarchical three-dimensional
organisation. Among these levels of compartmentalisation, topologically associating …