[HTML][HTML] Artificial intelligence (AI) and big data in cancer and precision oncology

Z Dlamini, FZ Francies, R Hull, R Marima - Computational and structural …, 2020 - Elsevier
Artificial intelligence (AI) and machine learning have significantly influenced many facets of
the healthcare sector. Advancement in technology has paved the way for analysis of big …

[HTML][HTML] Breast cancer in low-middle income countries: abnormality in splicing and lack of targeted treatment options

FZ Francies, R Hull, R Khanyile… - American journal of …, 2020 - ncbi.nlm.nih.gov
Breast cancer is a common malignancy among women worldwide. Regardless of the
economic status of a country, breast cancer poses a burden in prevention, diagnosis and …

Health disparities and triple-negative breast cancer in African American women: a review

LA Newman, LM Kaljee - JAMA surgery, 2017 - jamanetwork.com
Importance Variation in cancer incidence and outcome has well-documented correlations
with racial/ethnic identity. In the United States, the possible genetic and ancestral hereditary …

Age influences on the molecular presentation of tumours

CH Li, S Haider, PC Boutros - Nature communications, 2022 - nature.com
Cancer is often called a disease of aging. There are numerous ways in which cancer
epidemiology and behaviour change with the age of the patient. The molecular bases for …

A review of cancer genetics and genomics studies in Africa

SO Rotimi, OA Rotimi, B Salhia - Frontiers in oncology, 2021 - frontiersin.org
Cancer is the second leading cause of death globally and is projected to overtake infectious
disease as the leading cause of mortality in Africa within the next two decades. Cancer is a …

Prevalence of Clinically Relevant Germline BRCA Variants in a Large Unselected South African Breast and Ovarian Cancer Cohort: A Public Sector Experience

NC Van der Merwe, HME Combrink, KS Ntaita… - Frontiers in …, 2022 - frontiersin.org
Breast cancer is a multifaceted disease that currently represents a leading cause of death in
women worldwide. Over the past two decades (1998–2020), the National Health Laboratory …

Genetics and Genomics of Breast Cancer: update and translational perspectives

M Biancolella, B Testa, LB Salehi, MR D'Apice… - Seminars in cancer …, 2021 - Elsevier
In the recent years the rapid scientific innovation in the evaluation of the individual's genome
have allowed the identification of variants associated with the onset, treatment and …

BRCA1 and BRCA2 pathogenic sequence variants in women of African origin or ancestry

TM Friebel, IL Andrulis, J Balmaña, AM Blanco… - Human …, 2019 - Wiley Online Library
Abstract BRCA1 and BRCA2 (BRCA1/2) pathogenic sequence variants (PSVs) confer
elevated risks of multiple cancers. However, most BRCA1/2 PSVs reports focus on …

Breast cancer germline genetic counseling and testing for populations of African heritage globally: a scoping review on research, practice, and bioethical …

Y Iwai, K Toumbou, T Zuze, JS Morgan… - JCO Global …, 2023 - ascopubs.org
PURPOSE Despite the disproportionately high risk of breast cancer among women of
African heritage, little is known about the facilitators and barriers to implementing germline …

Genetics of breast cancer in African populations: a literature review

A Abbad, H Baba, H Dehbi… - Global health …, 2018 - cambridge.org
Breast cancer (BC) is one of the most complex, diverse and leading cause of death in
women worldwide. The present investigation aims to explore genes panel associated with …