Liver sinusoidal endothelial cells (LSECs) form the wall of the hepatic sinusoids. Unlike
other capillaries, they lack an organized basement membrane and have cytoplasm that is …

Liver sinusoidal endothelial cells (LSECs) line the low shear, sinusoidal capillary channels
of the liver and are the most abundant non-parenchymal hepatic cell population. LSECs do …

Liver sinusoidal endothelial cells (LSEC) form a unique barrier between the liver sinusoids
and the underlying parenchyma, and thus play a crucial role in maintaining metabolic and …

Acute vascular endothelial dysfunction is a central event in the pathogenesis of sepsis,
increasing vascular permeability, promoting activation of the coagulation cascade, tissue …

Infections, due to a dysfunctional immune response, pose a great risk to patients with
decompensated cirrhosis and herald the beginning of the terminal phase of this disease …

Intercellular crosstalk among various liver cells plays an important role in liver fibrosis,
cirrhosis, and hepatocellular carcinoma (HCC). Capillarization of liver sinusoidal endothelial …

Hepatocellular carcinoma (HCC) is characterized by high prevalence, morbidity, and
mortality. Liver cancer is the sixth most common cancer worldwide; and its subtype, HCC …

Liver sinusoidal endothelial cells (LSECs) are highly specialized endothelial cells that
represent the interface between blood cells on one side and hepatocytes on the other side …

Primary liver cancer is one of the leading causes of cancer-related deaths worldwide. China
has more than 55% liver cancer cases globally. The development of hepatocellular …

Background Translational failures in anti-adhesion molecule therapies after stroke reveal
the necessity of developing new strategies that not only interrupt leukocyte recruitment but …