Traumatic central nervous system (CNS) injury, which includes both traumatic brain injury
(TBI) and spinal cord injury (SCI), is associated with irreversible loss of neurological function …

Hyperosmotic therapy is commonly used to treat intracranial hypertension in traumatic brain
injury patients. Unfortunately, hyperosmolality also affects other organs. An increase in …

Hypoxia inducible factor 1 alpha (HIF-1α) is involved in regulating the biological functions of
neuronal death after traumatic brain injury (TBI), and attaches importance in the …

To repair the blood—brain barrier (BBB) after traumatic brain injury (TBI) remains a
multidisciplinary challenge. No first-line drugs are available. Here, we reported a novel and …

Neuroinflammatory processes mediated by microglial activation and subsequent neuronal
damage are the hallmarks of traumatic brain injury (TBI). As an inhibitor of the macrophage …

Abstract Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease mainly
affecting upper and lower motoneurons. Several functionally heterogeneous genes have …

With growing and ageing populations, the incidence of dementia is expected to triple
globally by 2050. In the absence of effective drugs to treat or reverse the syndrome, dietary …

Cerebral ischemia/reperfusion (I/R) injury is a complex pathophysiological process that can
lead to neurological function damage and the formation of cerebral infarction. The p38 …

For developing an effective interventional approach and treatment modality for PM2. 5, the
effects of omega-3 fatty acids on alleviating inflammation and attenuating lung injury …

The neurovascular unit (NVU) is composed of neurons, glial cells, and blood vessels. NVU
dysfunction involves the processes of neuroinflammation, and microcirculatory disturbances …