The increased awareness of the potential role played by mineral and bone disorder in the
appearance of cardiovascular disease in renal patients has produced research efforts aimed …

The impressive cardiovascular morbidity and mortality of chronic kidney disease (CKD)
patients is attributable in a significant proportion to endothelial dysfunction (ED), arterial …

Background Cardiovascular morbidity and mortality remains excessive in patients with
chronic kidney disease. The association of vascular changes with regulators of …

Background. Expression of bone proteins resulting from transdifferentiation of vascular
smooth muscle cells into osteoblasts suggests that vascular calcifications are a bioactive …

Background. Extra-skeletal calcification and disordered phosphate metabolism are
hallmarks of chronic kidney disease–mineral bone disorder (CKD–MBD). Osteoprotegerin …

Results Higher serum OPG levels were associated with older age, female gender, greater
systolic BP, lower estimated GFR, and lower serum albumin. OPG was not associated with …

Prognosis, risk stratification and monitoring the effects of treatment are fundamental
elements in the decision-making process when implementing prevention strategies for …

Patients with chronic kidney disease (CKD) have an extremely poor cardiovascular
outcome. Arterial stiffness, a strong independent predictor of survival in CKD, is connected to …

Background Osteoprotegerin is a cytokine involved in bone metabolism as well as vascular
calcification and atherogenesis. Although circulating osteoprotegerin levels are robustly …

Introduction Vascular calcification and stiffness are associated with higher mortality and
cardiovascular disease in hemodialysis patients, but the underlying mechanism is not well …