[HTML][HTML] β-Sitosterol as a promising anticancer agent for chemoprevention and chemotherapy: mechanisms of action and future prospects

H Wang, Z Wang, Z Zhang, J Liu, L Hong - Advances in Nutrition, 2023 - Elsevier
Cancer is one of the primary causes of death worldwide, and its incidence continues to
increase yearly. Despite significant advances in research, the search for effective and …

Molecular mechanism of β-sitosterol and its derivatives in tumor progression

X Bao, Y Zhang, H Zhang, L Xia - Frontiers in oncology, 2022 - frontiersin.org
β-Sitosterol (SIT), a white powdery organic substance with a molecular formula of C29H50O,
is one of the most abundant naturally occurring phytosterols in plants. With a chemical …

Anticancer activity and other biomedical properties of β‐sitosterol: Bridging phytochemistry and current pharmacological evidence for future translational approaches

S Nandi, A Nag, S Khatua, S Sen… - Phytotherapy …, 2024 - Wiley Online Library
Sterols, including β‐sitosterol, are essential components of cellular membranes in both plant
and animal cells. Despite being a major phytosterol in various plant materials …

Protective effects of proanthocyanidin-rich fraction from red rice germ and bran on lung cell inflammation via inhibition of NF-κB/NLRP3 inflammasome pathway

W Semmarath, K Srisawad, P Arjsri, S Umsumarng… - Nutrients, 2023 - mdpi.com
The activation of the NLRP3 inflammasome pathway during infectious pathogen-induced
immunopathology can lead to chronic inflammation and various adverse health outcomes …

Hesperetin from Root Extract of Clerodendrum petasites S. Moore Inhibits SARS-CoV-2 Spike Protein S1 Subunit-Induced NLRP3 Inflammasome in A549 Lung Cells …

P Arjsri, K Srisawad, S Mapoung… - International Journal of …, 2022 - mdpi.com
Inhibition of inflammatory responses from the spike glycoprotein of SARS-CoV-2 (Spike) by
targeting NLRP3 inflammasome has recently been developed as an alternative form of …

[HTML][HTML] Antitumor potential of Hedyotis diffusa Willd: a systematic review of bioactive constituents and underlying molecular mechanisms

X Han, X Zhang, Q Wang, L Wang, S Yu - Biomedicine & Pharmacotherapy, 2020 - Elsevier
Cancer is a major cause of death in the world. Chemotherapy can extend the life of cancer
patients to some extent, but the quality of life is reduced. Therefore, the quest for more …

A delve into the pharmacological targets and biological mechanisms of Paederia foetida Linn.: a rather invaluable traditional medicinal plant

MK Sarma, D Saha, BK Das, T Das, S Azizov… - Naunyn-Schmiedeberg's …, 2023 - Springer
Drug development from herbal medicines or botanical sources is believed to have a
prominent role in the exploration of novel counteractive drugs that has sparked much …

Targeting spike glycoprotein S1 mediated by NLRP3 inflammasome machinery and the cytokine releases in A549 lung epithelial cells by nanocurcumin

C Chittasupho, K Srisawad, P Arjsri, R Phongpradist… - Pharmaceuticals, 2023 - mdpi.com
Chronic inflammation and tissue damage can result from uncontrolled inflammation during
SARS-CoV-2 or COVID-19 infections, leading to post-acute COVID conditions or long …

[HTML][HTML] A review on phytochemistry of Paederia foetida Linn

PP Dutta, K Marbaniang, S Sen, BK Dey… - Phytomedicine Plus, 2023 - Elsevier
Abstract Introduction Paederia foetida Linn. is a widespread plant of the Rubiaceae family
distributed in temperate and tropical Asia. The plant has a distinct characteristic of emitting a …

Molecular basis of prostate cancer and natural products as potential chemotherapeutic and chemopreventive agents

B Bai, Q Chen, R Jing, X He, H Wang, Y Ban… - Frontiers in …, 2021 - frontiersin.org
Prostate cancer is the second most common malignant cancer in males. It involves a
complex process driven by diverse molecular pathways that closely related to the survival …