Pre-eclampsia is a complication of pregnancy that is associated with substantial maternal
and fetal morbidity and mortality. The disease presents with new-onset hypertension and …

Preeclampsia is a devastating medical complication of pregnancy that can lead to significant
maternal and fetal morbidity and mortality. It is currently believed that there is abnormal …

Interventions to prevent pregnancy complications have been largely unsuccessful. We
suggest this is because the foundation for a healthy pregnancy is laid prior to the …

The causes of preeclampsia remain one of the great medical mysteries of our time. This
syndrome is thought to occur in 2 stages with abnormal placentation leading to a maternal …

From the time when they were first described in the 1970s by the group of Johnstone and
Stahl, exosomes are a target of constant research. Exosomes belong to the family of …

In the past decade, extracellular vesicles (EVs) have been recognized as potent vehicles of
intercellular communication, both in prokaryotes and eukaryotes. This is due to their capacity …

Clinical treatments have stalled in certain diseases due to a lack of proper therapeutic
delivery systems. Recent studies have identified exosomes for their potential use as cell-free …

While there is considerable contemporary interest in elucidating the role of placenta-derived
extracellular vesicles in normal and complicated pregnancies and their utility as biomarkers …

An improved mechanistic understanding of the adaptational processes mounted during
mammalian reproduction is emerging. Intricate pathways occurring at the fetomaternal …

Body fluids contain surprising numbers of cell-derived vesicles which are now thought to
contribute to both physiology and pathology. Tools to improve the detection of vesicles are …