Molecular mechanisms of antibiotic resistance revisited

EM Darby, E Trampari, P Siasat, MS Gaya… - Nature Reviews …, 2023 - nature.com
Antibiotic resistance is a global health emergency, with resistance detected to all antibiotics
currently in clinical use and only a few novel drugs in the pipeline. Understanding the …

[HTML][HTML] Antibacterial mechanisms of cinnamon and its constituents: A review

NG Vasconcelos, J Croda, S Simionatto - Microbial pathogenesis, 2018 - Elsevier
Background In the current healthcare environment, an alarming rise in multi-drug resistant
bacterial infections has led to a global health threat. The lack of new antibiotics has created …

Distinct Roles of Outer Membrane Porins in Antibiotic Resistance and Membrane Integrity in Escherichia coli

U Choi, CR Lee - Frontiers in microbiology, 2019 - frontiersin.org
A defining characteristic of Gram-negative bacteria is the presence of an outer membrane,
which functions as an additional barrier inhibiting the penetration of toxic chemicals, such as …

Structure, function and regulation of Pseudomonas aeruginosa porins

S Chevalier, E Bouffartigues, J Bodilis… - FEMS microbiology …, 2017 - academic.oup.com
Pseudomonas aeruginosa is a Gram-negative bacterium belonging to the γ-proteobacteria.
Like other members of the Pseudomonas genus, it is known for its metabolic versatility and …

Microplastics exacerbate co-occurrence and horizontal transfer of antibiotic resistance genes

X Yu, ZC Zhou, X Shuai, Z Lin, Z Liu, J Zhou… - Journal of hazardous …, 2023 - Elsevier
Microplastic pollution is a rising environmental issue worldwide. Microplastics can provide a
niche for the microbiome, especially for antibiotic-resistant bacteria, which could increase …

Adaptive and mutational resistance: role of porins and efflux pumps in drug resistance

L Fernández, REW Hancock - Clinical microbiology reviews, 2012 - Am Soc Microbiol
The substantial use of antibiotics in the clinic, combined with a dearth of new antibiotic
classes, has led to a gradual increase in the resistance of bacterial pathogens to these …

Envelope stress responses: balancing damage repair and toxicity

AM Mitchell, TJ Silhavy - Nature Reviews Microbiology, 2019 - nature.com
The Gram-negative envelope is a complex structure that consists of the inner membrane, the
periplasm, peptidoglycan and the outer membrane, and protects the bacterial cell from the …

Surveying membrane landscapes: a new look at the bacterial cell surface

T Lithgow, CJ Stubenrauch, MPH Stumpf - Nature Reviews Microbiology, 2023 - nature.com
Recent studies applying advanced imaging techniques are changing the way we
understand bacterial cell surfaces, bringing new knowledge on everything from single-cell …

Molecular basis of bacterial outer membrane permeability revisited

H Nikaido - Microbiology and molecular biology reviews, 2003 - Am Soc Microbiol
Gram-negative bacteria characteristically are surrounded by an additional membrane layer,
the outer membrane. Although outer membrane components often play important roles in …

Mechanisms of survival, responses and sources of Salmonella in low-moisture environments

S Finn, O Condell, P McClure, A Amézquita… - Frontiers in …, 2013 - frontiersin.org
Some Enterobacteriaceae possess the ability to survive in low-moisture environments for
extended periods of time. Many of the reported food-borne outbreaks associated with low …