An extracellular matrix composed of a layered meshwork of β-glucans, chitin, and
mannoproteins encapsulates cells of the yeast Saccharomyces cerevisiae. This organelle …

The fungal cell wall is a complex structure composed of chitin, glucans and other polymers,
and there is evidence of extensive cross-linking between these components. The wall …

INTRODUCTION Total synthesis of designer chromosomes and genomes is a new
paradigm for the study of genetics and biological systems. The Sc2. 0 project is building a …

Cell size is an important adaptive trait that influences nearly all aspects of cellular
physiology. Despite extensive characterization of the cell-cycle regulatory network, the …

Appropriate cell number and organ size in a multicellular organism are determined by
coordinated cell growth, proliferation, and apoptosis. Disruption of these processes can …

The cyclin dependent kinase Cdk1 controls the cell cycle, which is best understood in the
model organism S. cerevisiae. Research performed during the past decade has significantly …

Members of the NDR (nuclear Dbf2-related) protein-kinase family are essential components
of pathways that control important cellular processes, such as morphological changes …

The mammalian MST kinase family, which is related to the Hippo kinase in Drosophila
melanogaster, includes five related proteins: MST1 (also called STK4), MST2 (also called …

To analyze the dynamics of protein complexes during the yeast cell cycle, we integrated
data on protein interactions and gene expression. The resulting time-dependent interaction …

Cell-cycle control of transcription seems to be a universal feature of proliferating cells,
although relatively little is known about its biological significance and conservation between …