Electrical stimulation system based on electroactive biomaterials for bone tissue engineering
Traumatic injuries can lead to large bone defects under extreme conditions, which usually
take a long recovery period, while the prognosis is poor. Endogenous electric field, as one …
take a long recovery period, while the prognosis is poor. Endogenous electric field, as one …
Calcium phosphate ceramics in bone tissue engineering: a review of properties and their influence on cell behavior
Calcium phosphate ceramics (CPCs) have been widely used as biomaterials for the
regeneration of bone tissue because of their ability to induce osteoblastic differentiation in …
regeneration of bone tissue because of their ability to induce osteoblastic differentiation in …
The mechanosensitive Piezo1 channel is required for bone formation
W Sun, S Chi, Y Li, S Ling, Y Tan, Y Xu, F Jiang, J Li… - elife, 2019 - elifesciences.org
Mechanical load of the skeleton system is essential for the development, growth, and
maintenance of bone. However, the molecular mechanism by which mechanical stimuli are …
maintenance of bone. However, the molecular mechanism by which mechanical stimuli are …
[PDF][PDF] The material and biological characteristics of osteoinductive calcium phosphate ceramics
Z Tang, X Li, Y Tan, H Fan… - Regenerative biomaterials, 2018 - academic.oup.com
The discovery of osteoinductivity of calcium phosphate (Ca-P) ceramics has set an enduring
paradigm of conferring biological regenerative activity to materials with carefully designed …
paradigm of conferring biological regenerative activity to materials with carefully designed …
Disorders of bone remodeling
X Feng, JM McDonald - Annual Review of Pathology …, 2011 - annualreviews.org
The skeleton provides mechanical support for stature and locomotion, protects vital organs,
and controls mineral homeostasis. A healthy skeleton must be maintained by constant bone …
and controls mineral homeostasis. A healthy skeleton must be maintained by constant bone …
Calcium/calmodulin signaling controls osteoblast growth and differentiation
M Zayzafoon - Journal of cellular biochemistry, 2006 - Wiley Online Library
Ca2+ is a ubiquitous intracellular messenger responsible for controlling numerous cellular
processes including fertilization, mitosis, neuronal transmission, contraction and relaxation …
processes including fertilization, mitosis, neuronal transmission, contraction and relaxation …
Current application of beta-tricalcium phosphate in bone repair and its mechanism to regulate osteogenesis
Large segmental bone loss and bone resection due to trauma and/or the presence of tumors
and cysts often results in a delay in healing or non-union. Currently, the bone autograft is the …
and cysts often results in a delay in healing or non-union. Currently, the bone autograft is the …
Regulation of osteoclast differentiation and function by the CaMK-CREB pathway
K Sato, A Suematsu, T Nakashima… - Nature medicine, 2006 - nature.com
Abstract Calcium (Ca2+) signaling is essential for a variety of cellular responses and higher
biological functions. Ca2+/calmodulin-dependent kinases (CaMKs) and the phosphatase …
biological functions. Ca2+/calmodulin-dependent kinases (CaMKs) and the phosphatase …
[HTML][HTML] PVA/pectin composite hydrogels inducing osteogenesis for bone regeneration
Z Hu, J Cheng, S Xu, X Cheng, J Zhao, ZWK Low… - Materials Today Bio, 2022 - Elsevier
Hydrogels composed from biomolecules have gained great interests as biomaterials for
tissue engineering. However, their poor mechanical properties limit their application …
tissue engineering. However, their poor mechanical properties limit their application …
Pannexin 3 functions as an ER Ca2+ channel, hemichannel, and gap junction to promote osteoblast differentiation
M Ishikawa, T Iwamoto, T Nakamura, A Doyle… - Journal of Cell …, 2011 - rupress.org
The pannexin proteins represent a new gap junction family. However, the cellular functions
of pannexins remain largely unknown. Here, we demonstrate that pannexin 3 (Panx3) …
of pannexins remain largely unknown. Here, we demonstrate that pannexin 3 (Panx3) …