Parkinson's disease (PD) is a complicated neurodegenerative disease attributed to
multifactorial changes. However, its pathological mechanism remains undetermined …

Parkinson's disease (PD) is a progressive brain disorder that interferes with activities of
normal life. The main pathological feature of this disease is the loss of more than 80% of …

The α-Klotho is an anti-aging protein that, when overexpressed, extends the life span in
humans and mice. It has an anti-inflammatory and protective action on renal cells by …

Ouabain (OUA) is a cardiac glycoside that binds to Na+, K+-ATPase (NKA), a conserved
membrane protein that controls cell transmembrane ionic concentrations and requires ATP …

Aim To investigate the protective effect of microRNA-34a (miR-34a) on propofol-induced
neurotoxicity and cognitive dysfunction. Methods After SH-SY5Y cells were treated with …

Prion diseases are neurodegenerative pathologies characterized by the accumulation of a
protease-resistant form of the cellular prion protein named prion protein scrapie (PrPSc) in …

α-Synuclein (α-Syn) is intimately linked to the etiology of Parkinson's Disease, as mutations
and even subtle increases in gene dosage result in early onset of the disease. However …

Parkinson's disease (PD) is a complex neurodegenerative disorder characterized by the
progressive loss of dopaminergic neurons, leading to motor and non-motor symptoms …

Alleviating microglia-mediated neuroinflammation bears great promise to reduce
neurodegeneration. Nicotinamide phosphoribosyltransferase (NAMPT) may exert cytokine …

The three-dimensional (3D) culture of neural cells in Matrigel, a thermoresponsive, self-
assembling, extracellular matrix hydrogel, holds promise for modelling neurodegenerative …