Cartilage is a connective tissue in the skeletal system and has limited regeneration ability
and unique biomechanical reactivity. The growth and development of cartilage can be …

It is well-known that collagen is the most abundant protein in the human body; however,
what is not often appreciated is its fascinating physical chemistry and molecular physics. In …

Biomechanical changes to the collagen fibrillar architecture in articular cartilage are
believed to play a crucial role in enabling normal joint function. However, experimentally …

Mechanical stimuli regulate the chondrogenic differentiation of mesenchymal stem cells and
the homeostasis of chondrocytes, thus affecting implant success in cartilage tissue …

The purpose of our study was to analyze abnormal neural regeneration activity in the cornea
through means of confocal microscopy in rheumatoid arthritis patients with concomitant dry …

Mineralized collagen fibrils (MCFs) are the fundamental building blocks of bone tissue and
contribute significantly to the mechanical behavior of bone. However, it is still largely …

Tissue repair requires a complex cascade of events mediated by a variety of cells, proteins,
and matrix molecules; however, the healing cascade can be easily disrupted by numerous …

The bone-cartilage unit (BCU) is a universal feature in diarthrodial joints, which is
mechanically-graded and subjected to shear and compressive strains. Changes in the BCU …

Injurious mechanical loading of articular cartilage and associated lesions compromise the
mechanical and structural integrity of joints and contribute to the onset and progression of …

Glucocorticoid (or steroid) induced osteoporosis (GIOP) is the leading form of secondary
osteoporosis, affecting up to 50% of patients receiving chronic glucocorticoid therapy. Bone …