Endocytosis is a complex process whereby cell surface proteins, lipids and fluid from the
extracellular environment are packaged, sorted and internalized into cells. Endocytosis is …

For nearly 50 years the proximal tubule (PT) has been known to reabsorb, process, and
either catabolize or transcytose albumin from the glomerular filtrate. Innovative techniques …

Targeted drug delivery in cancer typically focuses on maximising the endocytosis of drugs
into the diseased cells. However, there has been less focus on exploiting the differences in …

The beneficial or deleterious effects of nanomedicines emerge from their complex
interactions with intracellular pathways and their subcellular fate. Moreover, the dynamic …

Ferroptosis, a newly characterized form of regulated cell death, is induced by excessive
accumulation of lipid peroxidation catalyzed by intracellular bioactive iron. Increasing …

Background Macropinocytosis, an important nutrient-scavenging pathway in certain cancer
cells, allows cells to compensate for intracellular amino acid deficiency under nutrient-poor …

Endocytosis mediates the uptake of extracellular proteins, micronutrients and
transmembrane cell surface proteins. Importantly, many viruses, toxins and bacteria hijack …

Macropinocytosis is defined as an actin-dependent but coat-and dynamin-independent
endocytic uptake process, which generates large intracellular vesicles (macropinosomes) …

Intracellular organelles change their size during trafficking and maturation. This requires the
transport of ions and water across their membranes. Macropinocytosis, a ubiquitous form of …

Simple Summary Boron neutron capture therapy (BNCT) is a tumor-selective particle
radiotherapy. It combines preferential boron accumulation in tumors and neutron irradiation …