Recreating human organ–level function in vitro is a rapidly evolving field that integrates
tissue engineering, stem cell biology, and microfluidic technology to produce 3D organoids …

Living cells can sense mechanical forces and convert them into biological responses.
Similarly, biological and biochemical signals are known to influence the abilities of cells to …

Human mesenchymal stromal cells (hMSCs) are mechanically sensitive undergoing
phenotypic alterations when subjected to shear stress, cell aggregation, and substrate …

Blood vessels are constantly exposed to hemodynamic forces in the form of cyclic stretch
and shear stress due to the pulsatile nature of blood pressure and flow. Endothelial cells …

Nanoparticles are commonly administered through systemic injection, which exposes them
to the dynamic environment of the bloodstream. Injected nanoparticles travel within the …

Mechanical forces are crucial to the regulation of cell and tissue morphology and function. At
the cellular level, forces influence cytoskeletal organization, gene expression, proliferation …

Vascular endothelial cells (ECs) form a semiselective barrier for macromolecules and cell
elements regulated by dynamic interactions between cytoskeletal elements and cell …

Nitric oxide production in response to flow-dependent shear forces applied on the surface of
endothelial cells is a fundamental mechanism of regulation of vascular tone, peripheral …

Background—Prognosis of ischemic cardiomyopathy still remains poor because of the lack
of effective treatments. To develop a noninvasive therapy for the disorder, we examined the …

Introduction Low-intensity shock wave therapy (LI-ESWT) has been reported as an effective
treatment in men with mild and moderate erectile dysfunction (ED). Aim The aim of this study …