Mastocytosis is a hematologic neoplasm characterized by expansion and focal
accumulation of neoplastic mast cells (MC) in diverse organs, including the skin, bone …

Mastocytosis is a term used to denote a heterogeneous group of conditions defined by the
expansion and accumulation of clonal (neoplastic) tissue mast cells in various organs. The …

Advanced systemic mastocytosis (AdvSM) is a rare hematologic neoplasm driven by the KIT
D816V mutation and associated with poor survival. This phase 1 study (NCT02561988) …

Systemic mastocytosis (SM) has greatly benefited from the broad application of precision
medicine techniques to hematolymphoid neoplasms. Sensitive detection of the recurrent KIT …

Mastocytosis is a myeloid neoplasm defined by expansion and focal accumulation of clonal
mast cells (MCs) in one or more organs. The disease exhibits a complex pathology and may …

Advanced systemic mastocytosis (AdvSM) is a rare myeloid neoplasm associated with poor
overall survival (OS). This study (NCT04695431) compared clinical outcomes between …

Mast cells (MCs) contribute to the pathogenesis of a multitude of diseases that include MC-
driven disorders such as urticaria, type I allergies, and mastocytosis as well as autoimmune …

Indolent systemic mastocytosis (ISM) is the most prevalent form of systemic mastocytosis.
Many patients with ISM suffer from mast cell (MC) mediator-related symptoms. In a small …

Mast cells (MCs) are versatile effector cells of the immune system, characterized by a large
content of secretory granules containing a variety of inflammatory mediators. They are …

Mastocytosis is a hematopoietic neoplasm defined by abnormal expansion and focal
accumulation of clonal tissue mast cells in various organ-systems. The disease exhibits a …