Inflammation is a crucial component of various stress-induced responses that contributes to
the pathogenesis of major depressive disorder (MDD). Depressive-like behavior (DLB) is …

Stress is an important risk factor for modern chronic diseases, with distinct influences in
males and females. The sex specificity of the mammalian stress response contributes to the …

Astrocytes contribute to brain inflammation in neurological disorders but the molecular
mechanisms controlling astrocyte reactivity and their relationship to neuroinflammatory …

Multiple sclerosis (MS) is the most common chronic inflammatory and neurodegenerative
disease of the central nervous system (CNS). An interesting feature that this debilitating …

As is reported, the incidence and prevalence of depression are higher in women than in
men, but the cause of this sex difference remains elusive. Although recent studies implicated …

Background Depressed patients present increased plasma levels of lipopolysaccharide
(LPS) and neuroinflammatory alterations. Here, we determined the neuroimmune effects of …

To investigate the effects of ketamine on glucose uptake and glucose transporter (GLUT)
expression in depressive-like mice. After HA1800 cells were treated with ketamine, 2-[N-(7 …

The present study aims to investigate the influence of sex/age on depressive-like behaviors
in lipopolysaccharide (LPS)-challenged mice model, and explore the underlying …

Doxycycline (DOXY) is a second-generation tetracycline with anti-inflammatory and
neuroprotective effects. A proinflammatory profile seems to predict the severity of depressive …

Background Arsenic metabolism enzymes can affect the toxic effects of arsenic. However,
the effects of different genders on the metabolites and metabolic enzymes in liver arsenic …