Does the naked emperor parable apply to current perceptions of the contribution of renin angiotensin system inhibition in hypertension?

CM Ferrario, A Saha, JL VonCannon… - Current Hypertension …, 2022 - Springer
Abstract Purpose of Review To address contemporary hypertension challenges, a critical
reexamination of therapeutic accomplishments using angiotensin converting enzyme …

Engineering nanosystems for transdermal delivery of antihypertensive drugs

M Fan, W Liu, L Zhao, L Nie, Y Wang - Pharmaceutical …, 2024 - Taylor & Francis
Abstract: To control hypertension, long-term continuous antihypertensive therapeutics are
required and five classes of antihypertensive drugs are frequently involved, including …

The changing landscape of drug clinical trials on cardiometabolic diseases in China, 2009–2021

C Li, J Hao, Y Zheng, C Wang, J Yang, W Wang… - Diabetology & Metabolic …, 2023 - Springer
Background Cardiometabolic disease is a clinical syndrome characterized by multiple
metabolic disorders, with atherosclerosis as the core and cardiovascular and …

Angiotensin-(1-12): does it exist? A critical evaluation in humans, rats, and mice

AF Rodrigues, O Domenig, M Poglitsch, M Bader… - …, 2024 - Am Heart Assoc
BACKGROUND: Angiotensin-(1-12), measured by a self-developed, polyclonal antibody-
based radioimmunoassay, has been suggested to act as an alternative precursor of …

[PDF][PDF] Increased CaMKII activation and contrast changes of cardiac β1-and β3-Adrenergic signaling pathways in a humanized angiotensinogen model of hypertension

X Sun, J Cao, Z Chen, Y Liu, JL VonCannon, HJ Cheng… - Heliyon, 2023 - cell.com
Abstract Aims Upregulation of Ca 2+/calmodulin-dependent protein kinase II (CaMKII)
contributes to the pathogenesis of cardiovascular disease, including hypertension …

[HTML][HTML] Is renal dysfunction amplified in an arginine vasopressin induced rat model of preeclampsia?

S Ramdin, T Naicker, S Baijnath, N Govender - Reproductive Biology, 2024 - Elsevier
Renal dysfunction is important in preeclampsia (PE) pathophysiology and has not been fully
explored in the arginine vasopressin (AVP) rat model of PE. This study aimed to determine …

Internalization of Angiotensin-(1–12) in Adult Retinal Pigment Epithelial-19 Cells

S Ahmad, KN Wright, JL VonCannon… - Journal of Ocular …, 2023 - liebertpub.com
Purpose: Angiotensin-(1–12)[Ang-(1–12)] serves as a primary substrate to generate
angiotensin II (Ang II) by angiotensin-converting enzyme and/or chymase suggests it may be …

Renin–angiotensin–aldosterone system inhibitors. New and old approaches

CM Ferrario, JL VonCannon, KN Wright, S Ahmad - Angiotensin, 2023 - Elsevier
Renin–angiotensin–aldosterone system inhibitors. New and old approaches - ScienceDirect
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A Ying-Yang Perspective on the Renin Angiotensin System in Cardiovascular Disease

S Ahmad, CM Ferrario - The Renin Angiotensin System in Cardiovascular …, 2023 - Springer
The renin angiotensin system (RAS) plays a critical role in the regulation of the homeostatic
control of arterial pressure, body fluids, and cardiovascular adjustments to metabolic needs …

Cardiovascular peptide hormones-special edition

TV Braga, E Mervaala, R Santos, M Bader - Peptides, 2023 - pubmed.ncbi.nlm.nih.gov
Cardiovascular Peptide Hormones - Special edition Cardiovascular Peptide Hormones -
Special edition Peptides. 2023 Jul 6;171062. doi: 10.1016/j.peptides.2023.171062. Online …