Nanotechnology-based approaches to promote lymph node targeted delivery of cancer vaccines

R He, J Zang, Y Zhao, H Dong, Y Li - ACS Biomaterials Science & …, 2022 - ACS Publications
Vaccines are a promising immunotherapy that awakens the human immune system to inhibit
and eliminate cancer with fewer side effects compared with traditional radiotherapy and …

[HTML][HTML] An Overview of DNA Vaccines Development Studies Against Toxoplasma gondii

C Gül, T Karakavuk, M Karakavuk… - Turkiye …, 2022 - turkiyeparazitolderg.org
Toxoplasma gondii (T. gondii) is an obligate intracellular parasite that can infect almost all
warm-blooded animals, including humans, and one-third of the global population is thought …

Immunogenicity of a xenogeneic multi-epitope HER2+ breast cancer DNA vaccine targeting the dendritic cell restricted antigen-uptake receptor DEC205

A Gül, M Döşkaya, H Can, M Karakavuk, M Anıl-İnevi… - Vaccine, 2022 - Elsevier
Breast cancer was ranked first in global cancer incidence in 2020, and HER2
overexpression in breast cancer accounts for 20–30% of breast cancer patients. Current …

Development of multistage recombinant protein vaccine formulations against toxoplasmosis using a new chitosan and porin based adjuvant system

S Parmaksız, A Gül, SE Alak, M Karakavuk… - International Journal of …, 2022 - Elsevier
Toxoplasmosis is a global health problem affecting both human and animal populations.
The lack of effective treatment makes the development of a vaccine against toxoplasmosis …

[HTML][HTML] Heterologous Prime-Boost Immunization with DNA Vaccine and Modified Recombinant Proteins Enhances Immune Response against Trueperella pyogenes …

T Huang, K Zhao, X Song, T Song, X Wang, X Zhang… - Vaccines, 2022 - mdpi.com
Trueperella pyogenes (T. pyogenes) is a crucial opportunistic pathogen normally causing
mastitis, abscesses and pneumonia in economically important ruminants. Although only one …

A novel DNA vaccine encoding the SRS13 protein administered by electroporation confers protection against chronic toxoplasmosis

C Gül, A Gül, T Karakavuk, SE Alak, M Karakavuk… - Vaccine, 2024 - Elsevier
Toxoplasma gondii is an obligate intracellular parasite that can infect a variety of mammals
including humans and causes toxoplasmosis. Unfortunately, a protective and safe vaccine …

[HTML][HTML] Protective Efficacy of a Novel DNA Vaccine with a CL264 Molecular Adjuvant against Toxoplasma gondii in a Murine Model

K Ju, Y Zhang, Z Xu, L Li, X Zhao, H Zhou - Vaccines, 2024 - mdpi.com
Toxoplasmosis is a significant global zoonosis with devastating impacts, and an effective
vaccine against toxoplasmosis for humans has not yet been developed. In this study, we …

[HTML][HTML] In Vitro Evaluation Reveals Effect and Mechanism of Artemether against Toxoplasma gondii

Q Xu, YY Duan, M Pan, QW Jin, JP Tao, SY Huang - Metabolites, 2023 - mdpi.com
Due to the limited effectiveness of existing drugs for the treatment of toxoplasmosis, there is
a dire need for the discovery of new therapeutic options. Artemether is an important drug for …

[HTML][HTML] Biotechnological based recombinant protein vaccines developed against toxoplasmosis

T Karakavuk, C Gül, M Karakavuk, A Gül… - Turkiye …, 2022 - turkiyeparazitolderg.org
Toxoplasma gondii (T. gondii) that can infect most warm-blooded animals and humans, is an
obligate intracellular apicomplexan parasite with a wide host range. About one-third of the …

Toxoplasma gondii'ye Karşı Geliştirilen DNA Aşılarına Genel Bir Bakış

C Gül, T Karakavuk, M Karakavuk… - Türkiye Parazitolojii …, 2022 - search.proquest.com
Abstract Toxoplasma gondii (T. gondii), insan dahil hemen hemen tüm sıcakkanlı hayvanlan
enfekte edebilen zorunlu hücre içi bir parazittir ve küresel nüfusun üçte birinin bu parazit ile …