Functional foods as potential therapeutic options for metabolic syndrome

L Brown, H Poudyal, SK Panchal - Obesity reviews, 2015 - Wiley Online Library
Obesity as part of metabolic syndrome is a major lifestyle disorder throughout the world.
Current drug treatments for obesity produce small and usually unsustainable decreases in …

Position statement on nutrition therapy for overweight and obesity: nutrition department of the Brazilian association for the study of obesity and metabolic syndrome …

RB Pepe, AM Lottenberg, CTH Fujiwara… - Diabetology & metabolic …, 2023 - Springer
Obesity is a chronic disease resulting from multifactorial causes mainly related to lifestyle
(sedentary lifestyle, inadequate eating habits) and to other conditions such as genetic …

Carotid body denervation prevents the development of insulin resistance and hypertension induced by hypercaloric diets

MJ Ribeiro, JF Sacramento, C Gonzalez… - Diabetes, 2013 - Am Diabetes Assoc
Increased sympathetic activity is a well-known pathophysiological mechanism in insulin
resistance (IR) and hypertension (HT). The carotid bodies (CB) are peripheral …

Polyphenol-and caffeine-rich postfermented pu-erh tea improves diet-induced metabolic syndrome by remodeling intestinal homeostasis in mice

X Gao, Q Xie, P Kong, L Liu, S Sun, B Xiong… - Infection and …, 2018 - Am Soc Microbiol
Postfermented Pu-erh tea (PE) protects against metabolic syndrome (MS), but little is known
regarding its underlying mechanisms. Animal experiments were performed to determine …

Caffeine consumption prevents memory impairment, neuronal damage, and adenosine A 2A receptors upregulation in the hippocampus of a rat model of sporadic …

J Espinosa, A Rocha, F Nunes… - Journal of …, 2013 - content.iospress.com
Abstract Intracerebroventricular (icv) streptozotocin (STZ) administration induces
pathological and behavioral alterations similar to those observed in Alzheimer's disease …

Elevated norepinephrine may be a unifying etiological factor in the abuse of a broad range of substances: alcohol, nicotine, marijuana, heroin, cocaine, and caffeine

PJ Fitzgerald - Substance abuse: research and treatment, 2013 - journals.sagepub.com
A wide range of commonly abused drugs have effects on the noradrenergic neurotransmitter
system, including alterations during acute intoxication and chronic use of these drugs. It is …

Spatial memory impairments in a prediabetic rat model

E Soares, RD Prediger, S Nunes, AA Castro, SD Viana… - Neuroscience, 2013 - Elsevier
Diabetes is associated with an increased risk for brain disorders, namely cognitive
impairments associated with hippocampal dysfunction underlying diabetic encephalopathy …

Development and validation of an insulin resistance model for a population with chronic kidney disease using a machine learning approach

CL Lee, WJ Liu, SF Tsai - Nutrients, 2022 - mdpi.com
Background: Chronic kidney disease (CKD) is a complex syndrome without a definitive
treatment. For these patients, insulin resistance (IR) is associated with worse renal and …

Bioelectronic modulation of carotid sinus nerve activity in the rat: a potential therapeutic approach for type 2 diabetes

JF Sacramento, DJ Chew, BF Melo, M Donegá… - Diabetologia, 2018 - Springer
Aims/hypothesis A new class of treatments termed bioelectronic medicines are now
emerging that aim to target individual nerve fibres or specific brain circuits in pathological …

Carotid body, insulin, and metabolic diseases: unraveling the links

SV Conde, JF Sacramento, MP Guarino… - Frontiers in …, 2014 - frontiersin.org
The carotid bodies (CB) are peripheral chemoreceptors that sense changes in arterial blood
O2, CO2, and pH levels. Hypoxia, hypercapnia, and acidosis activate the CB, which respond …