Reverse engineering approach: a step towards a new era of vaccinology with special reference to Salmonella

S Vij, R Thakur, P Rishi - Expert Review of Vaccines, 2022 - Taylor & Francis
Introduction Salmonella is responsible for causing enteric fever, septicemia, and
gastroenteritis in humans. Due to high disease burden and emergence of multi-and …

Prioritization of potential vaccine candidates and designing a multiepitope-based subunit vaccine against multidrug-resistant Salmonella Typhi str. CT18: A subtractive …

Y Chand, S Singh - Microbial Pathogenesis, 2021 - Elsevier
Salmonella enterica serovar Typhi (S. Typhi), a causative agent of typhoid fever, is a Gram-
negative, human-restricted pathogen that causes significant morbidity and mortality …

Genome-wide screening of vaccine targets prioritization and reverse vaccinology aided design of peptides vaccine to enforce humoral immune response against …

A Zeb, SS Ali, AK Azad, M Safdar, Z Anwar… - Computers in Biology …, 2021 - Elsevier
Campylobacter jejuni, gram-negative bacteria, is an infectious agent of foodborne disease-
causing bloody diarrhea, abdominal pain, fever, Guillain-Barré syndrome (GBS) and Miller …

[HTML][HTML] Development of a novel multi-epitope vaccine candidate against Streptococcus iniae infection in fish: an immunoinformatics study

A Forouharmehr, A Banan, A Jaydari - Archives of Razi Institute, 2022 - ncbi.nlm.nih.gov
Streptococcus Iniae infection is recognized as a disease with substantial economic losses,
infecting a wide range of fish species. The limitations of current vaccines and strategies have …

Identification of a Potential Vaccine against Treponema pallidum Using Subtractive Proteomics and Reverse-Vaccinology Approaches

S Khan, M Rizwan, A Zeb, MA Eldeen, S Hassan… - Vaccines, 2022 - mdpi.com
Syphilis, a sexually transmitted infection, is a deadly disease caused by Treponema
pallidum. It is a Gram-negative spirochete that can infect nearly every organ of the human …

Designing an efficient epitope-based vaccine conjugated with a molecular adjuvant against Bovine Babesiosis: A computational study

A Forouharmehr, N Nazifi, SM Mousavi, A Jaydari - Process Biochemistry, 2022 - Elsevier
The current study was designed to introduce an efficient epitope-based vaccine against
bovine babesiosis. Four immunogenic proteins of the Babesia. bovis including Trap, msa …

Combined oral vaccination with niche competition can generate sterilizing immunity against entero-pathogenic bacteria

V Lentsch, A Woller, C Moresi, SA Fattinger, S Aslani… - BioRXiv, 2022 - biorxiv.org
Widespread antimicrobial resistance generates an urgent need to develop better disease
prophylaxis for intestinal bacterial pathogens. While the first phase of infection with any …

Recent developments in systems biology and genetic engineering toward design of vaccines for TB

Sunita, Y Singh, G Beamer, X Sun… - Critical Reviews in …, 2022 - Taylor & Francis
Tuberculosis (TB) is one of the most prevalent diseases worldwide. The currently available
Bacillus Calmette-Guérin vaccine is not sufficient in protecting against pulmonary TB …

Design of a novel multiple epitope-based vaccine: an immunoinformatics approach to combat monkeypox

C Hayat, M Shahab, SA Khan, C Liang… - Journal of …, 2023 - Taylor & Francis
Monkeypox virus is an infectious agent that causes fever, Pneumonitis encephalitis, rash,
lymphadenopathy and bacterial infection. The current outbreak of monkeypox has …

Engineering an efficient poly-epitope vaccine against Toxoplasma gondii infection: a computational vaccinology study

A Forouharmehr - Microbial Pathogenesis, 2021 - Elsevier
Toxoplasmosis is a zoonotic disease caused by Toxoplasma gondii. Despite the importance
of toxoplasmosis, there is no comprehensive strategy to control this disease. Hence …