Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous
system (CNS) where immunopathology is thought to be mediated by myelin-reactive CD4+ T …

As our understanding of mycology progresses, the impact of fungal microbes on human
health has become increasingly evident. Candida albicans is a common commensal fungus …

The migration of circulating leukocytes into the central nervous system (CNS) is a key driver
of multiple sclerosis (MS) pathogenesis. The monoclonal antibody natalizumab proved that …

Multiple sclerosis (MS) is the most common chronic central nervous system inflammatory
disease. Individual courses are highly variable, with complete remission in some patients …

After natalizumab (NAT) cessation, some multiple sclerosis (MS) patients experience a
severe disease rebound. The rebound pathophysiology is still unclear; however, it has been …

Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system
(CNS) coined by inflammation and neurodegeneration. The actual cause of the …

Anti-tRNA autoantibodies are associated with interstitial lung disease (ILD), in at least two
clinical scenarios: the anti-synthetase syndrome (ASSD) and interstitial pneumonia with …

T helper (Th) 17 cells represent a unique subset of CD4+ T cells and are vital for clearance
of extracellular pathogens including bacteria and fungi. However, Th17 cells are also …

Objectives Multiple sclerosis (MS) is an autoimmune disease of the central nervous system.
Several effector mechanisms are involved in the immunopathology of MS and a variety of …

Background: Blood–barrier (BBB) breakdown and active inflammation are hallmarks of
relapsing multiple sclerosis (RMS), but the molecular events contributing to the development …