The pathogenesis of pterygium: current concepts and their therapeutic implications

J Chui, N Di Girolamo, D Wakefield, MT Coroneo - The ocular surface, 2008 - Elsevier
Pterygium is a disease of the ocular surface that is associated with chronic UV exposure and
is characterized by proliferation, inflammatory infiltrates, fibrosis, angiogenesis and …

The science of pterygia

JC Bradley, W Yang, RH Bradley, TW Reid… - British journal of …, 2010 - bjo.bmj.com
Pterygium is an ocular surface disease of humans attributed to chronic ultraviolet-B
exposure. Clinically, the condition involves invasive centripetal growth with associated …

Pathogenetic mechanisms and treatment options for ophthalmic pterygium: trends and perspectives

ET Detorakis, DA Spandidos - … journal of molecular …, 2009 - spandidos-publications.com
Pterygium is a fibrovascular lesion of the ocular surface that can display an aggressive
clinical behavior and, occasionally, threaten vision. Although there is no consensus on its …

Molecular basis of pterygium development

E Cardenas-Cantu, J Zavala, J Valenzuela… - Seminars in …, 2016 - Taylor & Francis
Pterygium pathogenesis is mainly related to UV light exposure. However, the exact
mechanisms by which it is formed have not been elucidated. Clinical advances in surgical …

The roles of mouse double minute 2 (MDM2) oncoprotein in ocular diseases: A review

H Jiang, J Luo, H Lei - Experimental Eye Research, 2022 - Elsevier
Abstract Mouse double minute 2 (MDM2), an E3 ubiquitin ligase and the primary negative
regulator of the tumor suppressor p53, cooperates with its structural homolog MDM4/MDMX …

Biomarkers in the occurrence and development of pterygium

S He, Z Wu - Ophthalmic Research, 2022 - karger.com
Pterygium is a kind of common conjunctival degeneration. The pathogenesis of pterygium is
complex, and various biomarkers provide new targets for treatment and prognosis …

Pterygium pathogenesis, actinic damage, and recurrence

JJY Chui, MT Coroneo - Pterygium, 2024 - taylorfrancis.com
Pterygium, perhaps the most obvious of the ophthalmohelioses (sun-related eye diseases)
1, 2 has proven to be an ophthalmic enigma. 3 It is potentially the Cinderella ocular disease …

[HTML][HTML] The role of substance P in the pathogenesis of pterygia

J Chui, N Di Girolamo, MT Coroneo… - … ophthalmology & visual …, 2007 - arvojournals.org
purpose. Pterygium is a prevalent ocular surface disorder thought to be triggered by chronic
ultraviolet damage to the limbus. One of the enigmatic features of pterygium is its wing-like …

Risk factors for recurrence in the treatment of recurrent pterygium

Y Kusano, S Den, T Yamaguchi, S Nishisako, M Fukui… - Cornea, 2024 - journals.lww.com
Purpose: The aim of this study was to identify the postoperative recurrence rate of recurrent
pterygium and to evaluate risk factors for the recurrence. Methods: This study was a …

[HTML][HTML] Relationship between the expression of cyclooxygenase-2 and survivin in primary pterygium

C Maxia, MT Perra, P Demurtas, L Minerba… - Molecular …, 2009 - ncbi.nlm.nih.gov
Purpose To investigate the expression of cyclooxygenase-2 (COX-2) in a group of 93
Ecuadorian primary pterygia and to evaluate a possible association between COX-2 and …