Osteosarcoma overview
BA Lindsey, JE Markel, ES Kleinerman - Rheumatology and therapy, 2017 - Springer
Osteosarcoma (OS) is the most common primary malignancy of bone and patients with
metastatic disease or recurrences continue to have very poor outcomes. Unfortunately, little …
metastatic disease or recurrences continue to have very poor outcomes. Unfortunately, little …
Metastatic osteosarcoma: a challenging multidisciplinary treatment
C Meazza, P Scanagatta - Expert review of anticancer therapy, 2016 - Taylor & Francis
Osteosarcoma is the most common malignant bone tumor, currently treated with pre-and
postoperative chemotherapy in association with the surgical removal of the tumor. About 15 …
postoperative chemotherapy in association with the surgical removal of the tumor. About 15 …
Genome-informed targeted therapy for osteosarcoma
Osteosarcoma is a highly aggressive cancer for which treatment has remained essentially
unchanged for more than 30 years. Osteosarcoma is characterized by widespread and …
unchanged for more than 30 years. Osteosarcoma is characterized by widespread and …
Immuno-genomic landscape of osteosarcoma
CC Wu, HC Beird, J Andrew Livingston… - Nature …, 2020 - nature.com
Limited clinical activity has been seen in osteosarcoma (OS) patients treated with immune
checkpoint inhibitors (ICI). To gain insights into the immunogenic potential of these tumors …
checkpoint inhibitors (ICI). To gain insights into the immunogenic potential of these tumors …
Future directions in the treatment of osteosarcoma
MW Bishop, KA Janeway, R Gorlick - Current opinion in pediatrics, 2016 - journals.lww.com
Future directions in the treatment of osteosarcoma : Current Opinion in Pediatrics Future
directions in the treatment of osteosarcoma : Current Opinion in Pediatrics Log in or Register …
directions in the treatment of osteosarcoma : Current Opinion in Pediatrics Log in or Register …
Prognostic factors in high-grade osteosarcoma of the extremities or trunk: an analysis of 1,702 patients treated on neoadjuvant cooperative osteosarcoma study group …
SS Bielack, B Kempf-Bielack, G Delling… - Journal of clinical …, 2002 - ascopubs.org
PURPOSE: To define prognostic factors for response and long-term outcome for a wide
spectrum of osteosarcomas, extending well beyond those of the typical young patient with …
spectrum of osteosarcomas, extending well beyond those of the typical young patient with …
Recent and ongoing research into metastatic osteosarcoma treatments
MA Harris, CJ Hawkins - International Journal of Molecular Sciences, 2022 - mdpi.com
The survival rate for metastatic osteosarcoma has not improved for several decades, since
the introduction and refinement of chemotherapy as a treatment in addition to surgery. Over …
the introduction and refinement of chemotherapy as a treatment in addition to surgery. Over …
[HTML][HTML] Survival and prognosis with osteosarcoma: outcomes in more than 2000 patients in the EURAMOS-1 (European and American Osteosarcoma Study) cohort
S Smeland, SS Bielack, J Whelan, M Bernstein… - European journal of …, 2019 - Elsevier
Background High-grade osteosarcoma is a primary malignant bone tumour mainly affecting
children and young adults. The European and American Osteosarcoma Study (EURAMOS) …
children and young adults. The European and American Osteosarcoma Study (EURAMOS) …
Primary metastatic osteosarcoma: presentation and outcome of patients treated on neoadjuvant Cooperative Osteosarcoma Study Group protocols
L Kager, A Zoubek, U Pötschger, U Kastner… - Journal of clinical …, 2003 - ascopubs.org
Purpose: To determine demographic data and define prognostic factors for long-term
outcome in patients presenting with high-grade osteosarcoma of bone with clinically …
outcome in patients presenting with high-grade osteosarcoma of bone with clinically …
A Sleeping Beauty forward genetic screen identifies new genes and pathways driving osteosarcoma development and metastasis
Osteosarcomas are sarcomas of the bone, derived from osteoblasts or their precursors, with
a high propensity to metastasize. Osteosarcoma is associated with massive genomic …
a high propensity to metastasize. Osteosarcoma is associated with massive genomic …