Genome editing by sequence-specific nucleases (SSNs) has revolutionized biology by
enabling targeted modifications of genomes. Although routine plant genome editing …

Genome editing technologies have progressed rapidly and become one of the most
important genetic tools in the implementation of pathogen resistance in plants. Recent years …

Disruption of susceptibility (S) genes in crops is an attractive breeding strategy for conferring
disease resistance,. However, S genes are implicated in many essential biological functions …

Grapevine (Vitis vinifera), one of the most economically important fruit crops in the world,
suffers significant yield losses from powdery mildew, a major fungal disease caused by …

Precise signalling between pollen tubes and synergid cells in the ovule initiates fertilization
in flowering plants. Contact of the pollen tube with the ovule triggers calcium spiking in the …

Sequence-specific nucleases have been applied to engineer targeted modifications in
polyploid genomes, but simultaneous modification of multiple homoeoalleles has not been …

To confer resistance against pathogens and pests in plants, typically dominant resistance
genes are deployed. However, because resistance is based on recognition of a single …

Loss-of-function mutations of one or more of the appropriate Mildew resistance locus o (Mlo)
genes are an apparently reliable “weapon” to protect plants from infection by powdery …

Many plant-associated microbes are pathogens that impair plant growth and reproduction.
Plants respond to infection using a two-branched innate immune system. The first branch …

While conceptual principles governing plant immunity are becoming clear, its systems-level
organization and the evolutionary dynamic of the host-pathogen interface are still obscure …