Clinical application of biomarkers is an integral component of transplant care. Clinicians and
scientists alike are in search of better biomarkers than the current serologic (serum …

Ex-vivo machine perfusion represents a superior organ preservation method over static cold
storage. There is still an urgent need for the optimization of the perfusion fluid and machine …

Kidney transplantation is the golden treatment for end-stage renal disease. Static cold
storage is currently considered the standard method of preservation, but dynamic …

Extracellular vesicles (EVs) play an important role in cell-to-cell communication by delivering
coding and non-coding RNA species and proteins to target cells. Recently, the therapeutic …

Background Hypothermic machine perfusion (HMP) is increasingly being used for extended
criteria kidney grafts. Pancreatic HMP is challenging because physiologically the pancreas …

In transplantation, hypothermic machine perfusion (HMP) has been shown to be superior to
static cold storage (SCS) in terms of functional outcomes. Ex vivo machine perfusion offers …

Lidocaine may be beneficial when added in solutions for the preservation of vascular grafts
or solid organs as it has anti-inflammatory, endothelial protective, and antithrombotic effects …

Abstract Purpose of Review In this review, we aim to introduce the concept of machine
perfusion of vascularized composite allografts (VCAs). We briefly discuss the basic elements …

目的探讨新型双肾常温机械灌注保存(normothermic machine perfusion, NMP)
系统对边缘供肾保存质量的意义及相关机制, 为其临床应用奠定理论基础. 方法选取小型猪10 …

Methods: Porcine kidneys underwent 4-h (SCS4, n= 4) or 52-h (SCS52, n= 4) SCS, followed
by 10 h of HMP and were then subjected to 2 h of isolated normothermic reperfusion (NRP) …