Gasdermin B (GSDMB) belongs to the gasdermin (GSDM) family which may adopt different
mechanisms of intramolecular domain interactions to modulate their lipid-binding and pore …

Pyroptosis is a type of inflammatory cell death that is triggered by the formation of pores on
the cell membrane by gasdermin (GSDM) family proteins. This process activates …

Gasdermin B (GSDMB) is part of the gasdermin (GSDM) family, and they use varying means
of domain interactions in molecules to adjust their pore‐forming and lipid‐binding actions …

In multiple sclerosis (MS), human endogenous retrovirus W family (HERV-W) envelope
protein, pHERV-W ENV, limits remyelination and induces microglia-mediated …

The review focuses on sulfated steroids that have been isolated from seaweeds, marine
sponges, soft corals, ascidians, starfish, and other marine invertebrates. Sulfur-containing …

Sphingolipids are a diverse family of complex lipids typically composed of a sphingoid base
bound to a fatty acid via amide bond. The metabolism of sphingolipids has long remained …

Muscle invasive bladder cancer (MIBC) is a heterogeneous disease with a high recurrence
rate and poor clinical outcomes. Molecular subtype provides a new framework for the study …

Background Acupuncture plays a critical role for the treatment of patients with Parkinson's
disease (PD), which is characterized by ferroptosis of dopaminergic neurons. It has been …

硫脑苷脂作为一种酸性鞘糖脂, 广泛存在于人体多种组织, 器官以及血液成分中,
其在多个系统中扮演着重要角色, 在不同疾病的发病机制中发挥着重要的病理生理学作用 …

This review is devoted to sulphated steroids that are produced by brittle star, starfish,
sponges, ascidian, snails and algae. Mono sulphated steroids have the pharmacological …