Use of Alcalase in the production of bioactive peptides: A review

VG Tacias-Pascacio, R Morellon-Sterling… - International journal of …, 2020 - Elsevier
This review aims to cover the uses of the commercially available protease Alcalase in the
production of biologically active peptides since 2010. Immobilization of Alcalase has also …

Proteases: An overview on its recent industrial developments and current scenario in the revolution of biocatalysis

V Aruna, V Chandrakala, G Angajala… - Materials Today …, 2023 - Elsevier
In recent years there is tremendous growth in the utilization of alkaline protease as an
industrial catalyst. The extensive usage of chemicals for various applications in industries is …

Enhanced clearing of wound-related pathogenic bacterial biofilms using protease-functionalized antibiotic nanocarriers

PJ Weldrick, MJ Hardman… - ACS applied materials & …, 2019 - ACS Publications
Biofilms are prevalent in chronic wounds and once formed are very hard to remove, which is
associated with poor outcomes and high mortality rates. Biofilms are comprised of surface …

Utilization of tilapia processing waste for the production of fish protein hydrolysate

JFX Silva, K Ribeiro, JF Silva, TB Cahú… - Animal feed science and …, 2014 - Elsevier
Abstract Viscera and carcasses represent 60–70% of whole fish body weight, and this
processing waste is a known source of bioactive molecules, including proteases. These …

Enhancement of alkaline protease activity and stability via covalent immobilization onto hollow core-mesoporous shell silica nanospheres

ASS Ibrahim, AA Al-Salamah, AM El-Toni… - International journal of …, 2016 - mdpi.com
The stability and reusability of soluble enzymes are of major concerns, which limit their
industrial applications. Herein, alkaline protease from Bacillus sp. NPST-AK15 was …

Facile synthesis of alcalase-inorganic hybrid nanoflowers used for soy protein isolate hydrolysis to improve its functional properties

AH Memon, R Ding, Q Yuan, Y Wei, H Liang - Food chemistry, 2019 - Elsevier
In this work, a facile approach was developed to synthesized alcalase-inorganic hybrid
nanocomposite (alcalase@ CaHPO 4) by immobilizing alcalase with calcium hydrogen …

Whey protein isolate hydrolysates obtained with free and immobilized Alcalase: Characterization and detection of residual allergens

TB Pessato, NC de Carvalho, OL Tavano… - Food Research …, 2016 - Elsevier
Protein antigenicity can be reduced by enzymatic hydrolysis, which can be performed either
by free or immobilized enzyme. The immobilized enzyme is removed from the reaction …

Cellulase immobilized by sol–gel entrapment for efficient hydrolysis of cellulose

M Ungurean, C Paul, F Peter - Bioprocess and biosystems engineering, 2013 - Springer
Abstract Cellulase from Trichoderma reesei (Celluclast 1.5 L, Novozyme) was immobilized
by sol–gel encapsulation, using binary or ternary mixtures of tetramethoxysilane (TMOS) …

Cooperativity of covalent attachment and ion exchange on alcalase immobilization using glutaraldehyde chemistry: Enzyme stabilization and improved proteolytic …

S Ait Braham, F Hussain… - Biotechnology …, 2019 - Wiley Online Library
Alcalase was scarcely immobilized on monoaminoethyl‐N‐aminoethyl (MANAE)‐agarose
beads at different pH values (< 20% at pH 7). The enzyme did not immobilize on MANAE …

Bacillus Swezeyi B2 Strain: A Novel Alkaliphilic Bacterium Producer of Alkaline-, Thermal, Oxidant-, and Surfactant-Stable Protease, Extremely Efficient in Detergency

M Elhamdi, S Ghorbel, N Hmidet - Current Microbiology, 2023 - Springer
Proteolytic enzymes that are currently used to meet industrial demand are usually derived
from Bacillus species. They find multiple technical applications, particularly they have been …