Overview of Castleman disease
A Dispenzieri, DC Fajgenbaum - Blood, The Journal of the …, 2020 - ashpublications.org
Castleman disease (CD) describes a group of at least 4 disorders that share a spectrum of
characteristic histopathological features but have a wide range of etiologies, presentations …
characteristic histopathological features but have a wide range of etiologies, presentations …
Castleman disease
Castleman disease (CD), a heterogeneous group of disorders that share morphological
features, is divided into unicentric CD and multicentric CD (MCD) according to the clinical …
features, is divided into unicentric CD and multicentric CD (MCD) according to the clinical …
Is severe COVID-19 a cytokine storm syndrome: a hyperinflammatory debate
P Mehta, DC Fajgenbaum - Current opinion in Rheumatology, 2021 - journals.lww.com
Hyperinflammation is a key component of severe COVID-19, residing underneath the
cytokine storm umbrella term, associated with poor outcomes. Better understanding of the …
cytokine storm umbrella term, associated with poor outcomes. Better understanding of the …
Novel insights and therapeutic approaches in idiopathic multicentric Castleman disease
DC Fajgenbaum - Blood, The Journal of the American Society …, 2018 - ashpublications.org
Castleman disease (CD) describes a heterogeneous group of hematologic disorders that
share characteristic lymph node histopathology. Patients of all ages present with either a …
share characteristic lymph node histopathology. Patients of all ages present with either a …
CXCL13 is a predictive biomarker in idiopathic multicentric Castleman disease
SK Pierson, L Katz, R Williams, M Mumau… - Nature …, 2022 - nature.com
Idiopathic multicentric Castleman disease (iMCD) is a rare and poorly-understood cytokine
storm-driven inflammatory disorder. Interleukin-6 (IL-6) is a known disease driver in some …
storm-driven inflammatory disorder. Interleukin-6 (IL-6) is a known disease driver in some …
Cancer-associated fibroblast-like fibroblasts in vocal fold leukoplakia suppress CD8+ T cell functions by inducing IL-6 autocrine loop and interacting with Th17 cells
Y Fang, M Chen, G Li, Y Yang, P He, J Chen, L Cheng… - Cancer Letters, 2022 - Elsevier
The characteristics of fibroblast cells in head and neck precancerous lesion and its ability to
secrete inflammatory cytokines and affect CD8+ T cell functions remain unclear. Herein, we …
secrete inflammatory cytokines and affect CD8+ T cell functions remain unclear. Herein, we …
Discovery and validation of a novel subgroup and therapeutic target in idiopathic multicentric Castleman disease
SK Pierson, S Shenoy, AB Oromendia… - Blood …, 2021 - ashpublications.org
Idiopathic multicentric Castleman disease (iMCD) is a poorly understood hematologic
disorder involving cytokine-induced polyclonal lymphoproliferation, systemic inflammation …
disorder involving cytokine-induced polyclonal lymphoproliferation, systemic inflammation …
Phase 2 study using oral thalidomide-cyclophosphamide-prednisone for idiopathic multicentric Castleman disease
L Zhang, A Zhao, M Duan, Z Li, X Cao… - Blood, The Journal …, 2019 - ashpublications.org
Idiopathic multicentric Castleman disease (iMCD) is a rare lymphoproliferative disorder. The
anti–interleukin 6 (IL-6) therapy siltuximab is not available everywhere, and is not effective …
anti–interleukin 6 (IL-6) therapy siltuximab is not available everywhere, and is not effective …
Treatment consistent with idiopathic multicentric Castleman disease guidelines is associated with improved outcomes
SK Pierson, MS Lim, G Srkalovic… - Blood …, 2023 - ashpublications.org
Idiopathic multicentric Castleman disease (iMCD) is a rare hematologic disorder with an
unknown etiology. Clinical presentation is heterogeneous, ranging from mild constitutional …
unknown etiology. Clinical presentation is heterogeneous, ranging from mild constitutional …
Idiopathic multicentric Castleman disease (iMCD)‐idiopathic plasmacytic lymphadenopathy: A distinct subtype of iMCD‐not otherwise specified with different clinical …
Y Gao, Y Liu, M Zhang, S Li… - British Journal of …, 2024 - Wiley Online Library
Idiopathic multicentric Castleman disease (iMCD) is subclassified into iMCD‐
thrombocytopenia, anasarca, reticulin fibrosis, renal dysfunction, organomegaly (TAFRO) …
thrombocytopenia, anasarca, reticulin fibrosis, renal dysfunction, organomegaly (TAFRO) …