Materials engineering strategies for cancer vaccine adjuvant development

X Zhang, B Yang, Q Ni, X Chen - Chemical Society Reviews, 2023 - pubs.rsc.org
Cancer vaccines have emerged as a powerful new tool for cancer immunotherapy.
Adjuvants are vaccine ingredients that enhance the strength, velocity, and duration of the …

[HTML][HTML] Cell membrane coated-nanoparticles for cancer immunotherapy

Y Zeng, S Li, S Zhang, L Wang, H Yuan, F Hu - Acta Pharmaceutica Sinica …, 2022 - Elsevier
Cancer immunotherapy can effectively inhibit cancer progression by activating the
autoimmune system, with low toxicity and high effectiveness. Some of cancer …

The tremendous biomedical potential of bacterial extracellular vesicles

J Xie, Q Li, F Haesebrouck, L Van Hoecke… - Trends in …, 2022 - cell.com
Bacterial extracellular vesicles (bEVs) are nano-sized, lipid membrane-delimited particles
filled with bacteria-derived components. They have important roles in the physiology and …

Extracellular‐vesicle‐based drug delivery systems for enhanced antitumor therapies through modulating the cancer‐immunity cycle

T Yong, Z Wei, L Gan, X Yang - Advanced Materials, 2022 - Wiley Online Library
Although immunotherapy harnessing activity of the immune system against tumors has
made great progress, the treatment efficacy remains limited in most cancers. Current …

In situ generation of micrometer-sized tumor cell-derived vesicles as autologous cancer vaccines for boosting systemic immune responses

Y Guo, SZ Wang, X Zhang, HR Jia, YX Zhu… - Nature …, 2022 - nature.com
Cancer vaccine, which can promote tumor-specific immunostimulation, is one of the most
important immunotherapeutic strategies and holds tremendous potential for cancer …

Bacteria-derived nanovesicles enhance tumour vaccination by trained immunity

G Liu, N Ma, K Cheng, Q Feng, X Ma, Y Yue… - Nature …, 2024 - nature.com
Trained immunity enhances the responsiveness of immune cells to subsequent infections or
vaccinations. Here we demonstrate that pre-vaccination with bacteria-derived outer …

Bacterial outer membrane vesicle based versatile nanosystem boosts the efferocytosis blockade triggered tumor-specific immunity

WR Zhuang, Y Wang, W Nie, Y Lei, C Liang… - Nature …, 2023 - nature.com
Efferocytosis inhibition is emerging as an attractive strategy for antitumor immune therapy
because of the subsequent leak of abundant immunogenic contents. However, the practical …

A heterogenic membrane-based biomimetic hybrid nanoplatform for combining radiotherapy and immunotherapy against breast cancer

P Pan, X Dong, Y Chen, JJ Ye, YX Sun, XZ Zhang - Biomaterials, 2022 - Elsevier
Radiotherapy is adopted to obliterate multiple malignant tumors clinically, which might also
induce antitumor immune response. However, traditional radiotherapy is not enough to …

Nanotechnology-empowered vaccine delivery for enhancing CD8+ T cells-mediated cellular immunity

G Liu, M Zhu, X Zhao, G Nie - Advanced drug delivery reviews, 2021 - Elsevier
After centuries of development, using vaccination to stimulate immunity has become an
effective method for prevention and treatment of a variety of diseases including infective …

Phytochemical engineered bacterial outer membrane vesicles for photodynamic effects promoted immunotherapy

WR Zhuang, Y Wang, Y Lei, L Zuo, A Jiang, G Wu… - Nano …, 2022 - ACS Publications
Cancer vaccines are emerging as an attractive modality for tumor immunotherapy. However,
their practical application is seriously impeded by the complex fabrication and unsatisfactory …