Valproic acid, a branching short chain fatty acid, is a popular drug to treat epilepsy and acts
as a mood-stabilizing drug. The obstruction of ion channels and Gamma Amino Butyrate …

Drug-induced liver injury (DILI) is a widespread and harmful disease closely linked to
mitochondrial and endoplasmic reticulum stress (ERS). Globally, severe drug-induced …

Background and purpose Despite many liver disorders, clinically useful drugs are scarce.
Moreover, the available therapies are facing the challenges of efficacy and safety. Alhagi …

This study aimed to investigate the potential role of gut microbiota in the hepatotoxicity of
sodium valproate (SVP) and the protective effect of ginsenoside compound K (G-CK) …

Introduction Persistent neuroinflammatory response after cauda equina injury (CEI) lowers
nociceptor firing thresholds, accompanied by pathological pain and decreasing extremity …

Valproic acid (VPA) is a very effective anticonvulsant and mood stabilizer with relatively few
side effects. Being an epigenetic modulator, it undergoes clinical trials for the treatment of …

Objective To investigate the effects of the anticonvulsant valproic acid (VPA) on salivary
glands in male rat using biochemical, functional, histomorphometric, and redox state …

Background: A wide range of medications may have a possible role in the development of
male-factor infertility (MFI), including various antineoplastic agents, testosterone/anabolic …

Traumatic spinal cord injury is a devastating disorder characterized by sensory, motor, and
autonomic dysfunction that severely compromises an individual's ability to perform activities …

Valproic acid (VPA) is a widely prescribed antiepileptic drug with various medicinal
efficacies. Accumulated evidence implied that prenatal exposure to VPA is highly associated …