Background and Purpose—The purpose of these guidelines is to provide an up-to-date
comprehensive set of recommendations in a single document for clinicians caring for adult …

Stroke is the leading cause of long term disability in developed countries and one of the top
causes of mortality worldwide. The past decade has seen substantial advances in the …

Intravenous thrombolysis is the only approved systemic reperfusion treatment for patients
with acute ischaemic stroke. These European Stroke Organisation (ESO) guidelines provide …

Background There is increasing interest in replacing alteplase with tenecteplase as the
preferred thrombolytic treatment for patients with acute ischaemic stroke. We aimed to …

Background Tenecteplase is a modified tissue plasminogen activator with pharmacological
and practical advantages over alteplase—which is currently the only approved thrombolytic …

Background Intravenous thrombolysis with alteplase bolus followed by infusion is a global
standard of care for patients with acute ischaemic stroke. We aimed to determine whether …

Background Mechanical thrombectomy (MT) has become the cornerstone of acute ischemic
stroke management in patients with large vessel occlusion (LVO). Objective To assist …

The treatment of acute ischemic stroke continues to advance. The mainstay of treatment
remains intravenous thrombolysis with alteplase. Recent studies demonstrated that later …

2018 Guidelines for the Early Management of Patients With Acute Ischemic Stroke: A
Guideline for Healthcare Professionals From the American Heart Association/American Stroke …

Background and Purpose—The purpose of these guidelines is to provide an up-to-date
comprehensive set of recommendations for clinicians caring for adult patients with acute …