The actions of neuromodulation are thought to mediate the ability of the mammalian brain to
dynamically adjust its functional state in response to changes in the environment. Altered …

The mesocorticolimbic pathway is canonically known as the" reward pathway." Embedded
within the center of this circuit is the striatum, a massive and complex network hub that …

The rapid and sensitive detection of di-(2-ethylhexyl) phthalate (DEHP) in plastics is of great
significance because of its toxicity and persistent contamination. Surface-enhanced Raman …

Neurochemical corelease has received much attention in understanding brain activity and
cognition. Despite many attempts, the multiplexed monitoring of coreleased neurochemicals …

How do we understand neuronal signaling in the brain, how neurons control behavior, or
how signaling malfunctions during disease? Neuroscientists might take two approaches …

Neuropeptides produce robust effects on behavior across species, and recent research has
benefited from advances in high-resolution techniques to investigate peptidergic …

Though the last decade has seen accelerated advances in techniques and technologies to
perturb neuronal circuitry in the brain, we are still poorly equipped to adequately dissect …

Immunotherapy targeting aggregated alpha-synuclein (αSYN) is a promising approach for
the treatment of Parkinson's disease. However, brain penetration of antibodies is hampered …

Microdialysis is a powerful sampling technique used to monitor small molecules in vivo.
Despite the many applications of microdialysis sampling, it is limited by the method of …

Monitoring of target analytes (eg, pharmaceuticals, endogenous compounds) present in
biological samples usually requires a preliminary step toward analyte isolation from …