Lipopolysaccharide (LPS [endotoxin]) is the principal component of the outer membrane of
Gram-negative bacteria. Recent studies have elucidated how LPS is recognized by …

The chronology and history of characterizing the aromatic hydrocarbon [Ah] battery is
reviewed. This battery represents the Ah receptor (AHR)-mediated control of at least six, and …

The promoter of the murine gene encoding inducible nitric oxide synthase (iNOS) contains
an NF-kappa B site beginning 55 base pairs upstream of the TATA box, designated NF …

The transcriptional activity of NF-κB is stimulated upon phosphorylation of its p65 subunit on
serine 276 by protein kinase A (PKA). The transcriptional coactivator CBP/p300 associates …

Molecular Control of Immune/Inflammatory Responses: Interactions Between Nuclear Factor-κB
and Steroid Receptor-Signaling Pathways | Endocrine Reviews | Oxford Academic Skip to …

CBP (CREB-binding protein) and p300 are versatile coactivators that link transcriptional
activators to the basal transcriptional apparatus. In the present study, we identify CBP and …

Rel/NF-κB proteins constitute a family of structurally-related transcription factors that are
regulated by interaction with a family of regulatory proteins, the IκB proteins. In this review …

Interferon-γ (IFNγ) and tumor necrosis factor-α (TNFα) cooperate to induce the expression of
many gene products during inflammation. The present report demonstrates that a portion of …

Interleukin-8 (IL-8), a member of the CXC chemokine family, is an important activator and
chemoattractant for neutrophils and has been implicated in a variety of inflammatory …

Nitric oxide synthase (NOS) catalyzes the production of nitric oxide (NO), a short-lived
radical gas with physiological or pathophysiological roles in nearly every organ system. The …