Effect and mechanism of quercetin or quercetin‐containing formulas against COVID‐19: From bench to bedside

JY Chen, TR Huang, SY Hsu, CC Huang… - Phytotherapy …, 2024 - Wiley Online Library
Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) has caused the global
coronavirus disease 2019 (COVID‐19) pandemic since 2019. Immunopathogenesis and …

Current advances in nanoformulations of therapeutic agents targeting tumor microenvironment to overcome drug resistance

S Fakhri, SZ Moradi, F Faraji, T Farhadi… - Cancer and Metastasis …, 2023 - Springer
The tumor microenvironment (TME) plays a pivotal role in cancer development and
progression. In this line, revealing the precise mechanisms of the TME and associated …

Biflavonoid quercetin protects against cyclophosphamide–induced organ toxicities via modulation of inflammatory cytokines, brain neurotransmitters, and astrocyte …

AY Onaolapo, FO Ojo, OJ Onaolapo - Food and chemical toxicology, 2023 - Elsevier
Background Cyclophosphamide use has been associated with increased oxidative stress in
cells and tissues. Quercetin's antioxidative properties make it of potential benefit in such …

Exploration of the effect and potential mechanism of quercetin in repairing spinal cord injury based on network pharmacology and in vivo experimental verification

W Shen, Q Liu, C Li, M Abula, Z Yang, Z Wang, J Cai… - Heliyon, 2023 - cell.com
Spinal cord injury (SCI) is a highly complex neurological disease, but there is no effective
repair method. Quercetin is a flavonol drug and has a variety of biological activities, such as …

Phytochemicals regulate cancer metabolism through modulation of the AMPK/PGC-1α signaling pathway

S Fakhri, SZ Moradi, SY Moradi, S Piri… - BMC cancer, 2024 - Springer
Background Due to the complex pathophysiological mechanisms involved in cancer
progression and metastasis, current therapeutic approaches lack efficacy and have …

Acellular spinal cord scaffold containing quercetin-encapsulated nanoparticles plays an anti-inflammatory role in functional recovery from spinal cord injury in rats

B Ebrahimi, T Mokhtari, N Ghaffari, M Adabi… - …, 2024 - Springer
Inflammatory responses play a crucial role in the pathophysiology of spinal cord injury (SCI)
and developing new approaches to establish an anti-inflammatory environment for the …

Development of new drug candidate for the inhibition of Nipah virus phosphoprotein by Quercetin Derivatives through in silico drug design approaches

A Berkane, N Kundu, AA Munia, B Chakrabarty… - Journal of the Indian …, 2024 - Elsevier
Abstract The Nipah virus (NiV) is a pathogenic infection that can cause a pandemic, hence
presenting a substantial risk to both human and animal communities. Despite its virulence …

Effect of liposomal complexes of quercetin-rich flavonoids from French Marigold (Tagetes patula L.) on Jurkat cell viability

G Janigashvili, E Shekiladze, I Chkhikvishvili… - Bioactive Compounds in …, 2024 - ffhdj.com
Background: Natural polyphenols are naturally used in traditional medicine to treat various
diseases. Despite their healthful properties, ingesting phenolic compounds in food form …