Introduction: The emergence of multidrug-resistant (MDR) infections has been extensively
observed worldwide and has become a priority issue over past decade. Tigecycline, a broad …

Tigecycline (TIG), the first member of glycylcycline bacteriostatic agents, has been approved
to treat complicated infections in the clinic because of its expanded-spectrum antibiotic …

Background. Emergence of extensively drug-resistant (XDR) bacteria has forced clinicians
to use off-label antimicrobial agents such as tigecycline. We present our experience on …

Introduction: Tigecycline, a derivative of minocycline, is an extended-spectrum antimicrobial
agent. It has a restricted approval field in children and the experience of its adoption in …

Conventional antibiotics used for the treatment of severe infections such as sepsis and
septic shock confer immunomodulatory benefits. However, the growing problem of multidrug …

The successful use of tigecycline in a 12-month old liver transplant recipient with extensively
drug-resistant Acinetobacter baumannii bacteremia is presented. Tigecycline serum …

Severe infection is a primary cause of mortality in children facing challenges from multidrug-
resistant (MDR) pathogens, particularly MDR Acinetobacter baumannii. Tigecycline has an …

Introduction Tigecycline (TGC) is effective for the infections caused by carbapenem‐resistant
gram‐negative bacteria (CRGNB) in adults, but it is not investigated systematically in …

Objective The aim of this study was to evaluate the efficacy and safety of salvage therapy of
tigecycline in critically ill children with infections caused by multidrug-resistant …

Tigecycline shows great antimicrobial activity against both Gram-positive and Gram-
negative bacteria, and has been considered to be an appropriate choice in controlling …