Chimeric antigen receptor (CAR) T cell is a novel approach, which utilizes anti-tumor
immunity for cancer treatment. As compared to the traditional cell-mediated immunity, CAR-T …

Regulatory T (Treg) cells play crucial roles in maintaining immune self-tolerance and
immune homeostasis, and closely associated with many human diseases. Recently, Treg …

The ocular surface is constantly exposed to environmental irritants, allergens and
pathogens, against which it can mount a prompt immune response to preserve its integrity …

Multiple sclerosis (MS) is an autoimmune disease which is characterized by neuroaxonal
degeneration in the central nervous system. Impaired function of regulatory T cells (Tregs) is …

MicroRNAs (miRNAs) are small RNA molecules with regulatory functions on the expression
of genes through binding directly to target messenger RNA (mRNA) transcripts, eventuating …

Arteriosclerosis (AS) presents a significant global health challenge, demanding innovative
therapeutic strategies. This review explores the potential of nanoparticles (NPs) and …

Periodontitis (PD), also known as gum disease, is a condition causing inflammatory bone
resorption and tooth loss. Regulatory T cells (Tregs) and regulatory B cells (Bregs) are vital …

We recently discovered that dectin-1-activated dendritic cells (DCs) drive potent T helper
(Th) 9 cell responses and antitumor immunity. However, the underlying mechanisms need to …

Several lines of evidence have linked a dysregulated inflammatory setting to the
pathogenesis of atherosclerosis, which is a form of chronic vascular inflammation. Various …

Recent studies demonstrated that a combination of the gut microbiome has the vital effect on
the efficacy of anticancer immune therapies. Regulatory effects of microbiota have been …