The flavivirus NS1 protein: molecular and structural biology, immunology, role in pathogenesis and application as a diagnostic biomarker
The flavivirus nonstructural glycoprotein NS1 is an enigmatic protein whose structure and
mechanistic function have remained somewhat elusive ever since it was first reported in …
mechanistic function have remained somewhat elusive ever since it was first reported in …
Endothelial dysfunction in dengue virus pathology
P Vervaeke, K Vermeire… - Reviews in medical …, 2015 - Wiley Online Library
Dengue virus (DENV) is a leading cause of illness and death, mainly in the (sub) tropics,
where it causes dengue fever and/or the more serious diseases dengue hemorrhagic fever …
where it causes dengue fever and/or the more serious diseases dengue hemorrhagic fever …
Naringenin-induced HO-1 ameliorates high glucose or free fatty acids-associated apoptosis via PI3K and JNK/Nrf2 pathways in human umbilical vein endothelial cells
J Feng, J Luo, L Deng, Y Zhong, X Wen, Y Cai… - International …, 2019 - Elsevier
Naringenin (NG), a flavanone extracted from various plants, has potent vasoprotective
effects likely related to the induction of heme oxygenase-1 (HO-1). In the current study, we …
effects likely related to the induction of heme oxygenase-1 (HO-1). In the current study, we …
Anti–Human Neutrophil Antigen-3a Induced Transfusion-Related Acute Lung Injury in Mice by Direct Disturbance of Lung Endothelial Cells
B Bayat, Y Tjahjono, A Sydykov, S Werth… - … , and vascular biology, 2013 - Am Heart Assoc
Objective—Antibodies against human neutrophil antigen-3a (HNA-3a) located on choline
transporter-like protein 2 induce severe transfusion-related acute lung injury (TRALI). This …
transporter-like protein 2 induce severe transfusion-related acute lung injury (TRALI). This …
Protein disulfide isomerase mediates dengue virus entry in association with lipid rafts
Dengue virus (DENV) causes a febrile disease, infecting around 50–100 million people
annually. The relationship between DENV proteins and host cellular responses during …
annually. The relationship between DENV proteins and host cellular responses during …
HLA class II antibodies induce necrotic cell death in human endothelial cells via a lysosomal membrane permeabilization-mediated pathway
A Aljabri, V Vijayan, M Stankov, C Nikolin… - Cell death & …, 2019 - nature.com
Antibody-mediated rejection (AMR) is the major cause of allograft loss after solid organ
transplantation. Circulating donor-specific antibodies against human leukocyte antigen …
transplantation. Circulating donor-specific antibodies against human leukocyte antigen …
Novel anti-thrombotic agent for modulation of protein disulfide isomerase family member ERp57 for prophylactic therapy
Protein disulfide isomerase (PDI) family members including PDI and ERp57 emerge as
novel targets for anti-thrombotic treatments, but chemical agents with selectivity remain to be …
novel targets for anti-thrombotic treatments, but chemical agents with selectivity remain to be …
[HTML][HTML] Correlation between serum levels of anti-endothelial cell autoantigen and anti-dengue virus nonstructural protein 1 antibodies in dengue patients
We have previously shown that anti–dengue virus nonstructural protein 1 (anti-DENV NS1)
antibodies cross-react with endothelial cells, and several autoantigens have been identified …
antibodies cross-react with endothelial cells, and several autoantigens have been identified …
[HTML][HTML] A highly conserved region between amino acids 221 and 266 of dengue virus non-structural protein 1 is a major epitope region in infected patients
MD Omokoko, S Pambudi… - The American journal …, 2014 - ncbi.nlm.nih.gov
The immune response to dengue virus (DENV) infection generates high levels of antibodies
(Abs) against the DENV non-structural protein 1 (NS1), particularly in cases of secondary …
(Abs) against the DENV non-structural protein 1 (NS1), particularly in cases of secondary …
Heme oxygenase-1 inhibits HLA class I antibody-dependent endothelial cell activation
E Zilian, H Saragih, V Vijayan, O Hiller, C Figueiredo… - Plos one, 2015 - journals.plos.org
Antibody-mediated rejection (AMR) is a key limiting factor for long-term graft survival in solid
organ transplantation. Human leukocyte antigen (HLA) class I (HLA I) antibodies (Abs) play …
organ transplantation. Human leukocyte antigen (HLA) class I (HLA I) antibodies (Abs) play …