Graphical abstract Abstract Infertility affects millions of couples worldwide. Oxidative stress
(OS) causes peroxidation of lipids and damage to spermatozoa, thus, reducing the quality of …

The metabolic expense of producing and operating neural tissue required for adaptive
behaviour is considered a significant selective force in brain evolution. In primates, brain …

The enzyme cytochrome c oxidase (CcO) or complex IV (EC 1.9. 3.1) is a large
transmembrane protein complex that serves as the last enzyme in the respiratory electron …

Oogenesis features an enormous increase in mitochondrial mass and mtDNA copy number,
which are required to furnish mature eggs with an adequate supply of mitochondria and to …

Studying animal models furthers our understanding of Parkinson's disease (PD)
pathophysiology by providing tools to investigate detailed molecular, cellular and circuit …

The metabolic properties of lymphomas derived from germinal center (GC) B cells have
important implications for therapeutic strategies. In this study, we have compared metabolic …

In vivo evidence for brain mitochondrial dysfunction in animal models of Huntington disease
(HD) is scarce. We applied the novel 17O magnetic resonance spectroscopy (MRS) …

Comparative neuroanatomical, developmental and functional evidence suggests that the
lateral division of the area dorsalis telencephali (Dl) of the teleost fish is homologous to the …

Defects in the respiratory chain, interfering with energy production in the cell, are major
underlying causes of mitochondrial diseases. In spite of this, the surprising variety of clinical …

Perturbations in metabolism are a well-documented but complex facet of schizophrenia
pathology. Optimal cellular performance requires the proper functioning of the electron …