In the very early stages of embryonic development, cells have the capability of dividing
indefinately and then differentiating into any type of cell in the body. Recent studies have …

In this overview of the pharmacology of the anticancer drug cyclophosphamide, a brief
history of the development of this drug from the general class of nitrogen mustards is …

Paraneoplastic cerebellar degeneration (PCD) is a heterogeneous group of disorders
characterized by subacute cerebellar ataxia, specific tumour types and (often) associated …

Objective To evaluate the safety and clinical efficacy of administering an anti–interleukin‐10
(anti–IL‐10) monoclonal antibody (mAb) to systemic lupus erythematosus (SLE) patients …

ContextManifestations of systemic lupus erythematosus (SLE) may in most patients be
ameliorated with medications that suppress the immune system. Nevertheless, there …

Background: Mesenchymal stem cells (MSCs) with their potential to differentiate into
mesodermal and non-mesodermal lineages have several immunomodulatory …

Abstract Rationale Phase I/II studies of autologous hematopoietic stem cell transplantation
(HSCT) for multiple sclerosis (MS) were initiated, based on results of experimental …

Objective: To analyse the durability of the responses after haematopoietic stem cell
transplantation (HSCT) for severe systemic sclerosis (SSc) and determine whether the high …

There were 21 patients with rapidly progressive multiple sclerosis (MS) treated on a phase
1/2 study of intense immune suppressive therapy and autologous hematopoietic stem cell …

Background Patients with systemic lupus erythematosus (SLE) who experience persistent
multiorgan dysfunction, despite standard doses of intravenous cyclophosphamide, represent …