Placentation is a reproductive adaptation that permits fetal growth and development within
the protected confines of the female reproductive tract. Through this important role, the …

Abstract The literature about Developmental Origins of Health and Disease (DOHaD)
studies is considerably growing. Maternal and paternal environment, during all the …

Background It is well established that obesity is associated with dysregulation of the ratio
between the two major adipokines leptin and adiponectin. Furthermore, it was recently …

Background Preeclampsia (PE) is a heterogeneous, hypertensive disorder of pregnancy,
with no robust biomarkers or effective treatments. We hypothesized that this heterogeneity is …

Inorganic arsenic is a well-established human carcinogen, able to induce genetic and
epigenetic alterations. More than 200 million people worldwide are exposed to arsenic …

Maternal diabetes and/or obesity in pregnancy are undoubtedly associated with later
disease-risk in the offspring. The placenta, interposed between the mother and the foetus, is …

Arsenic trioxide (As2O3) is a ubiquitous heavy metal in the environment. Exposure to this
toxin at low concentrations is unremarkable in developing organisms. Nevertheless …

As a food contaminant, oxidized oil or lipid oxidative products have been proven to exert
toxicological effects on the growth and development of animals and humans. Research …

Vitrification is increasingly used in assisted reproductive technology (ART) laboratories
worldwide, and potential vitrification‐induced risks require further exploration. The effect of …

Preeclampsia is a hypertensive disorder of pregnancy. Many studies have shown that
epigenetic mechanisms may play a role in preeclampsia. Moreover, our previous study …